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Natural Prodcast is a “fireside chat”-style podcast about … species unique and different from one another. They are incredibly important to medicine, the environment, and human health. As the JGI acts on …

… the most effective application, of marine molecules in general. DAN UDWARY: Maybe can you explain to our audience … in chemotherapy. Because 99.9% of cancer drugs are not so selective that they don’t have an impact on normal cells, … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … After I got my undergraduate degree, which was in general biology, I joined the Peace Corps. And when I was … spent your whole career as far as I’m aware working on specifically fungal natural products and fungal …

… was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria were. Dan … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis … energy and ecosystem management. The program aims to generate high-quality genomic datasets, particularly for … driven prioritization lists for laboratory isolation and genome sequencing of underexplored bacterial and archaeal …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary … systems are also everywhere – that there are some very specific patterns and shared DNA across all of these things. …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … that produces those. So it’s not a hard and fast rule, but, generally, animals do not have secondary metabolism that we … the drug. So for example, a lot of antibiotics will target specific parts of a cell wall. And so if you weaken a cell …

Menaka Wilhelm, who is the host of JGI’s other podcast, Genome Insider . If you’re a Genome Insider listener, then … I think for Natural Prodcast, I think the question that generally comes up that people come to me asking like is– … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we …

… critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by … al. (2019) Minimum Information about an Uncultivated Virus Genome (MIUViG).  Nature Biotech .  37 , 29–37 Roux S, et … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … comes to biocatalysis? You want your reactions to be very selective in terms of the products that they’re making. And … could have arisen from. DAN UDWARY: OK, so sort of a phylogenetic reconstruction kind of a thing. ALISON NARAYAN: …

… and uncultivated Bacteria and Archaea has steadily been widening since 2005. This gap is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …