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… RNA alongside. That really helps us to determine where genes start and end and really help improve our annotation. … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we … isolate genomes or single cell genomes, and analyze them without much help from JGI. So I would say, for these …
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… have gone on for a lot longer than we did, and I can say without reservation that Brian is one of the smartest people … mining-based approaches are that other than resistance genes, you have no way of knowing of whether or not a … is going to be active. And even if you do have resistance genes, it may not be better than something that already …
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… genomics existed. This is before we’re even thinking of genes and connecting genes to molecules, which is something that, you know, we … what’s going on. For sure. So, you know, I think one of the frontiers for us is connecting genes to chemistry to really …
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… extremely small genomes, like symbionts that can’t live without their host. They have no extra genes hanging around, they still dedicate 20-30% of their … with JGI to do genome sequencing, so to look for the genes that are involved in putting antibiotics together, …
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… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … Do you think that they always cluster or could the genes be separated on a genome? Dan: Oh yeah. It’s biology … want to think about them. That is one of the really big frontiers for the next stage of natural product drug …
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… rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …
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… team in collaboration with the JGI. Conserved Fungal Genes of Unknown Function offer a collection of fungal genes conserved across the fungal tree of life or its major …
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… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … in most fungi, biosynthetic gene clusters, which are the genes that do the biosynthesis of a secondary metabolite, … a really interesting biosynthetic pathway because fungal genes are cool. And if you like fungal genes, you should go …
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… of access and benefit sharing. So are you taking something without giving any benefit back to the owners of that … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … for antibacterial activity. And that was published in a Frontiers review paper. We tried to send this whole mega …
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… access your data, share with collaborators, and coordinate publication with JGI scientists. Synthetic DNA constructs …
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… team who have been really looking at ways to express genes in organisms that haven’t been used for really any … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …
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