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… For example, lipids– doesn’t matter if it has one extra carbon or two or one less, at the end of the day, it’s … You are not allowing any chemical diversification throughout this seven-enzyme pathway, because the only thing … it is more related to what JGI does, which is sequence genomes. And we just published last year in the Nature …

… so far no species or no strains known that really grow in freshwater. But they’re actually pretty orange, and they … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, … the evolution of secondary metabolite pathways as viewed through metagenome studies, and what more JGI and others can …

… on addressing critical energy and environmental challenges. Through innovative research in synthetic biology, the … that enhance biofuel production and biosystem design. High-throughput design and synthesis capabilities accelerate … a stepwise approach for strain development, requiring cycles of construct design, building, and characterization. …

… capabilities and functional genomics, scaling capacity through end-to-end automation — and further advancing … profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a multiplexed DAP-seq (multiDAP-seq) method allowing high-throughput processing of samples in 96-well plates on …

… and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific … SNP and short indel calls, rearrangement detection, population analysis Text file of SNPs (incl location in … SNP and short indel calls, rearrangement detection, population analysis. Text file of SNPs (incl location in …

… for improving fungal genomic resources empower students through isolation and genome sequencing of new fungal … Myco-Ed has:  ~50 lineages selected for sequencing 16 genomes released 20 members from 15 institutions 300+ … materials and bioinformatics exercises are freely available through the links below. Naturalist Myco Ed Fungal Genomics …

… scientific discovery at the DOE Office of Science through high performance computing (HPC) and data analysis.  … who might be interested in the project are coordinated through JGI’s Project Management Office.  At the completion … more customized analysis, the JGI also participates in publication of results. …

… from sediment cores in Antarctica that have– some of being carbon-dated to kind of 15,000, 150,000 years ago. So this … in the lab, you are only going to– you’re giving it certain nutrients. It’s only going to be able to generate so much … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… and a tool for predicting natural product structures from genomes. And I was writing grants furiously to try to get … started during my PhD. And then I actually found out, through a connection of my supervisor, that in parallel, … we actually add features as they come, and this is done through also a process where you say, OK, I want to build …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … could go down that route.  DAN: So the sun pierces down through the ice pretty well, is that right?  MARCY: It … DAN: What’s your opinion then on bioprospecting in sparse nutrient environments versus the tropics? Because like you …

… in. — DAN: So secondary metabolites. I kind of inferred through the stories I told you about geosmin, which is a … that’s good for them to grow in. They might have enough nutrients, but they might want to protect those nutrients … But… DAN: Yeah, there are a lot of ways to put together carbon molecules. Chemistry is pretty limitless. All right, …

… present in an environment that influence system behavior.  Through this identification, metabolomics enables functional … play in diverse biological systems, sheds light on nutrient cycling, and leads to the discovery of new …