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… Glavina del Rio , Danielle Graham , or Miranda Harmon-Smith DNA Synthesis projects: Miranda Harmon-Smith Metabolomics … You can visit the Products & Offerings section of our website for more details, including a downloadable … The majority of JGI projects come from the user community. Find out about …

… The mission of the Joint Genome Institute is to serve the scientific … relevant bioenergy and environmental problems.  The mission of the National Energy Research Scientific Computing Center … Science through high performance computing (HPC) and data analysis.  The DOE Systems Biology Knowledgebase ( KBase ) …

… to begin with. So transformation, or manipulation of the DNA of genes and bacteria, occurred much faster earlier than … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … Then you have to maybe improve some of your bioinformatic analysis. You don’t want to get clusters that are encoding …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the biological … into practical applications, including sustainable biofuels, biomaterials, natural products, and environmental …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … local environments, and so they don’t transfer a lot of DNA back and forth, especially across species. And so then … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … or whatever you’d like, whatever D– you can submit any DNA sequence really, and it will go through SMC’s pipeline. … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… has completed, your Project Manager will initiate analysis with the appropriate JGI analysis team. During this … access your data, share with collaborators, and coordinate publication with JGI scientists. Synthetic DNA constructs are also shipped at this time. Your Project …

… Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … niche in chemical enzymology. So, we talked about her JGI DNA synthesis project to explore the chemical capabilities … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … accepted proposals, sequencing, synthesis, metabolomics and analysis will be provided for free to the PI by the … provides customized analysis, the JGI also participates in publication of results. …

… The Synthetic Biology lab is divided into a DNA synthesis production group and a synthetic biology … as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … We focus our efforts on integrating database mining and sequence design with scaling the production of large, …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … a good catalog of what’s out there so that we can do more comparative analysis and maybe– I don’t know– start to put …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … in addition to sequencing, we offer metabolomics and also DNA synthesis. And we consider these capabilities a little … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we …