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… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … so I think we’ve covered a little bit about why they’re important. But one of the things I did want to make sure … metabolism is based on primary metabolism. It’s an evolution of primary metabolism. So a lot of the genes and …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. So sponges are … They’re at the base of the animal kingdom, in terms of evolution. Because they’re sitting there, they tend to have …

… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … doing development of projects on a project-by-project basis. And the more time has gone on, the more we’ve become … arc. And so, you know, definitely there has been a strong evolution in terms of the way the group thinks and that the …

… A genetic architecture that is characteristic of the sex … some, including shrub willow  Salix purpurea , employ the evolutionary strategy we are far more familiar with: … This work was supported by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to …

… pathway even if the genes are scrambled or altered in the chromosome. And so it becomes very difficult then to compare … especially across species that might be a little bit more genetically distant where the BGCs may have drifted but they … in more detail. Especially if you want to look at the evolution of these gene clusters, for example, you really …

… bit more into fungi and learning the differences of all the genetic differences and then expanded on on that knowledge … for thousands of years, but we’d like to start comparing evolution in real time to maybe like hypersaline … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… flowing– water flows into them and floods them on a regular basis. So they are full of terrestrial microbes. So they’re … Very familiar with working actinomycetes. We can also genetically manipulate them. We can do strain improvements. … school, then Frances Arnold’s papers came out, directed evolution, and Pim Stemmer. And at the time, I thought that …

… Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to the following Data … the need to have a limited and time-sensitive protection of certain types of data to support their use by those … PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and inter-organismal …

… The joint Critical Minerals and Materials call represents a unique … for researchers to request the capabilities and expertise of both the Joint Genome Institute and the Molecular Foundry … provides customized analysis, the JGI also participates in publication of results. Go here for additionial information, …

… Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on accessing sample-level reports and … sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the rate-limiting …