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… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … also be production, as we were mentioning before, of more complex secondary metabolites that an organism might want to … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … terms to those emerging features that are natural to this complex, then we might have a better understanding of what … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … wise maybe, what genome mining is, then, is looking at DNA sequence and trying to find the things that you want to … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, …

The IMG group owns and maintains integral components of JGI’s production workflow, and is responsible for the annotation and analysis of (meta)genomic, (meta)transcriptomic, and functional … (Alignment fraction, AF) have been computed for nearly 28,000 bacterial and archaeal genomes. By clustering genomes …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … biosynthetic gene clusters and genome size. And they’re so complex. There’s so much still to understand. Dan Udwary: … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … Metabolites Program offers users extensive genomics, DNA synthesis and metabolomics capabilities to identify, … based on extensive computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & …

… while, but Natural Prodcast is back again for another round of episodes. If you stick around for the next few months, … a lot more than that. The first one I would say is the complexity of the capabilities that we have and that you can … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we …

… functional genome annotation, improves understanding of the role small molecules play in diverse biological systems, sheds light on nutrient cycling, and leads to the … profiles from diverse biological and environmental samples using advanced liquid chromatography mass spectrometry …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … technologies available at JGI and EMSL such as DNA-SIP, Protein SIP, Flux Balance analysis with …

… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell … which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … and enzyme systems to do synthetic analoging of some really complex bioactive natural product molecules. It’s a wide …

See below for a list of Frequently Asked Questions about our proposal submission … proposals are subject to JGI policies on Data Release and Publication .   Except for applicants to the CSP New … data to well-annotated assembled genomes to synthesized DNA constructs to metabolomics data, depending on the …