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Natural Prodcast Episode 7: Ben Shen
… Right, because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … compound when they were first structurally resolved in the 1980s, they were known as the most toxic molecules, and that … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain …
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Draft genome sequence of marine alphaproteobacterial strain HIMB11, the first cultivated representative of a unique lineage within the Roseobacter clade possessing an unusually small genome
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Rex Malmstrom
… Microscale Applications group. Before joining the JGI in 2010, he made the first ever measurements of in situ growth rates and carbon consumption of SAR11 bacteria, the most abundant bacterial group in the ocean. … photosystem to unicellular marine predators.  PNAS 116 (41), 20574-20583 Couradeau, J.S. et al. 2019. Probing …
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DOE Metrics
…   Actual % Goal   FY 2026 Total   700.0     8,760     Q1 2026 175 313.081 179% 2,208 2,064 95.4% Q2 2026 175 243.806 139% 2,160 2,112 99.8% Q3 2026 175     2,164     Q4 2026 175     2,208   … 87.500 167.731 191% 2,140 2,184 102.1% Q4 2022 87.500 180.078 206% 2,164 2,208 102.0% *Includes Illumina and PacBio …
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Natural Prodcast Episode 4: Nancy Keller
… Wisconsin. Like we discussed in the primer podcasts ( part 1 here , part 2 here , and part 3 here ), which you should … first started out the natural product community was almost 100% bacterial. Only people working in mycotoxins worked … do you check if they’re there? Like we always talk about 16S for bacteria, but we don’t talk about it so easily with …
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Tanja Woyke Elected to American Academy of Microbiology
… the 68 new Fellows in the Class of 2020, selected from 118 nominees. The selection process for AAM Fellows is based … the AAM Fellows in this cohort. Go here for the full AAM news release. Woyke is also one of the organizers for the …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… relative of SOD is P. infestans , responsible for the mid-19th century Irish potato famine.   Shortly before the … . Science. 2006 Sep 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …
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Finding the Fermenters
… records of 8,350 organisms along with 4,355 genomes and 13.6 million genes. The results reveal that fermentative … more than 400 cultured rumen prokaryotes from the  Hungate1000 project . They also used the tool to predict possible … National Institute of Food and Agriculture grant 2018-67015-27495, the United States Department of Agriculture …
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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and … report the identification of active Cas enzymes – dubbed Cas14 – that target ssDNA. In contrast, the seminal Cas9 … while Burstein is now at Tel Aviv University. The Cas14 proteins are ~400–700 amino acids (aa) in size, half that …
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JGI announces 2025 Functional Genomics awardees
… and biotechnology innovation. Below find a list of the 11 researchers accepted for 2025.  Proposals are accepted …
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Natural Prodcast Episode 19: Bill Fenical
… that there was almost nothing. Now, this is back in the 1970s. So, I thought to myself, maybe I can use my … natural products in the ocean weren’t studied up until the 1970s. You know, I mean, people knew about plants’ chemistry ever since the isolation of morphine, 1870 or something like that. And so people were well aware …
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Streamlining Regulon Identification in Bacteria
… sequencing, they were able to identify the target genes of 11 sigma factors in Streptomyces coelicolor . The Impact As … and were able to identify the associated target genes in 11 of those. That work published in Nature Communications on … of Energy Office of Science under Contract No. DE-AC02-05CH11231 …
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