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… seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … do research. And it moved me to ask a simple question. In 1929, Alexander Fleming discovered a molecule called …

… 1) complementation of split luciferase (CSL) and, 2) bioluminescence resonance energy transfer (BRET)-based … databases for homologous YcgR proteins and chose a set of 92 proteins for functional characterization as candidate biosensors. These 92 homologues were synthesized as codon optimized sequences …

… Development of cell-free based expression platforms: Only 10-20% of BGCs are expressed under standard laboratory …

… CSP Large-Scale LOI #2 … FICUS Example #2 …

… impacts. The work is supported by NIH Common Fund grant 1U01DE034196-01. The JGI team, including Kyrpides, Camargo, and Roux, has … metagenome-assembled viral genomes ( Nature Biotechnology , 2021), geNomad , a tool for identifying mobile genetic …

… Notices Data Portal files will be inaccessible July 22–July 24 for computing upgrades . We regret any inconvenience. … Portal was replaced with the Data Portal and sunset in 2026. The Genome Portal was designed to provide unified access …

… acknowledge the use of deletion strains generated by Grant P01 GM-068087 “Functional Analysis of a Model Filamentous … Laboratory under US Department of Energy Contract DE-AC02-05CH11231, a Joint Genome Institute Community Science Program …

… is managed by UT-Battelle, LLC, under contract DE-AC05-00OR22725 for the DOE. The work conducted by the DOE Joint … of Tree and Forest Ecosystems (ARBRE) (ANR-11-LABX 0002 01 to F. Martin), JGI Community sequencing program project … and National Science Foundation (concept ID 10.13039/100000001; grant number DEB 1737898). …

… the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science 2017, Nature Microbiology 2018), discovery of … of Earth’s microbiomes. Nature Biotechnol . 39(4):499-509. Danko D. et al. (2021) A global metagenomic map of urban …

… Serve the Changing Planet (download a copy at jointgeno.me/2024StrategicPlan .) This plan aligns the DOE Office of … path, has previously proven successful; in the 2018-2023 five-year strategic plan, the JGI accomplished 90% …