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… Natural Prodcast is a “fireside chat”-style podcast about natural products and the science and scientists of secondary … capabilities for — secondary metabolism research, “Natural Prodcast” serves as an important line of communication to …

… The Synthetic Biology lab is divided into a DNA synthesis production group and a … in new technologies, in particular through adoption of lab automation enabling ever-higher levels of throughput. We …

… production is often not fully realized under standard laboratory conditions, with only a small portion of the … sustainable agriculture, and other fields reliant on natural product chemistry. These efforts will contribute to … platforms: Only 10-20% of BGCs are expressed under standard laboratory conditions by their native hosts. We are …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to … Anomaly” first described by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial … Bacteria and Archaea has steadily been widening since 2005. This gap is also reflected in the strongly biased …

… As a National User Facility, the JGI serves more than 2,500 users that predominately come from the public sector: … companies. Now the Department of Energy is uniting National Labs and industry, including User Facilities like the JGI, through its Genesis Mission. Launched in 2025, the initiative aims to accelerate scientific discovery, …

… With collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global challenges by … balance, to exploring the genetic basis of how plants have naturally adapted to varied climate and soil conditions … of secondary metabolites enhances our understanding of natural compounds that support disease resistance, with …

… qSIP quantifies incorporation of isotopes from labeled nutrients into biomass. When paired with … into DNA by active microbial populations (Hungate et al. 2015). With the development of high-throughput SIP (Nuccio et … Profile HMM search across all IMG metagenomes, capturing sequence diversity for proteins …

… Community Science Program (CSP), Facilities Integrating Collaborations for User Science (FICUS) initiative, Director’s … Embargo : A period in which data is not publicly available in JGI systems or outside repositories. Full access is granted to proposal PIs, Co-PIs, and collaborators of any given proposal. Third parties (often …

… biological insights from sequence data, employing IMG data and tools for comparative analysis, visualization … The Integrated Microbial Genomes & Microbiomes system ( IMG/M ) supports the annotation, comparative analysis, and … and publicly available datasets encompassing >150,000 isolate genomes, 230,000 metagenome-assembled genomes …

… into the science that the JGI makes possible. Each episode, host Menaka Wilhelm interviews researchers — JGI …

… stage. Generally, most users are able to work with Berkeley Lab.  However, users from certain countries (Iran, North … from other U.S. government agencies to work with Berkeley Lab, a process which can take 6 months or longer to obtain … to submit proposals, or to be listed as co-PIs or collaborators.   JGI’s standard User Agreement must be signed …

… to expand its habitat range. But at what cost?  A collaborative team led by researchers at the University of … in North America that has been the target of extensive natural sampling and field experiments due to its potential … surveying the genomic and phenotypic diversity across the natural range of switchgrass found that polyploidy has …