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… the idea of taking all the different natural products data that there is and putting things, coalescing them, so … with genomics and the kind of things that I do with genome mining. And figuring out how to put that together, I think, … that have no relation to anything. Dan Udwary: So with families of molecules, how far off are we from being able …
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… which the research is published. The JGI expects that the data produced by the facility result in scientific … below) for the generation of sequence or metabolomic data, DNA synthesized, and any other contributions, such as … and JGI together aim to publish the first analysis of data produced at the facility, provided this is done in a …
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… The JGI’s data stewardship expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and accessibility are critical …
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… or NPAtlas, a freely accessible natural products structure database, which is going to be just invaluable to the … field as it relates to structure elucidation and genome mining, and how we might start to better connect those two … natural products. And then we used a bunch of text mining tricks to try and extract all the relevant data from …
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… SMC – which is the new Secondary Metabolism Collaboratory data portal I’ve been working on with my colleagues Drew … melt is retained and concentrated. And we have a lot of the mining going on. And so there’s certain areas of the lake … is a comparative analysis tool that puts BGCs into gene families. And so we’re figuring out the best ways to do that …
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… easy to search for because there are patterns of domains, protein domains that you look for. And if you find those all … massive problems just as much as it brings about massive data into really interesting ways to look at our systems. … figuring out how to filter out noise from the metabolomics data. We’ve done a lot of work learning about how to use …
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… the broader community. We focus our efforts on integrating database mining and sequence design with scaling the production of … methods for converting digital information from sequence databases into biotechnological or environmental …
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… and ecological diversity of fungi and algae, examining both natural populations and engineered strains. This … ecosystems and industries. The program also explores microeukaryotic members of microbial communities, cataloging gene … sampling of fungi, laboratory analysis and genomics data exploration. …
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… DNA sequence – sequences for the genes that code for the proteins that produce secondary metabolites. Do you … to do something that the field refers to as “genome mining”. So, if you can sequence the DNA and actually … probably been since the last decade. We have a lot more data. Obviously, there’s been a lot of sequencing going on, …
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… Program combines large-scale, time-series metagenomic data with detailed characterization of model systems to … and metatranscriptomics, to metagenomics and metabolomics data, shedding light on microbial metabolism and activity in … environmental viral populations. Enabling microbiome data science: The JGI supports microbiome data science by …
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… an awesome job, in that respect. One of the natural product families we talk a lot about in this interview are the … on this: Most of the machinery in any living organism are proteins, which are made up of chains of amino acids. … proteins interact with each other. There’s a lot of leading data from excellent groups about specific interaction …
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… molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, … fuels the discovery of novel metabolites, genes, and proteins. It also enables exploration of energy and nutrient … program integrates cutting-edge metabolomics with genomic data to gain insights into how small molecules function …
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