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… research.  These efforts include exploration of the global diversity of alternative genetic codes (Science … et al. (2023) Unraveling the functional dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. … of bacterial and archaeal isolates expand coverage of the tree of life.  Nature Biotechnology  35(7):676-683 Schulz …

… natural products structure database, which is going to be just invaluable to the natural products community. It’s a … it in the show notes at  naturalprodcast.com . DAN: I also just want to say thanks to everyone listening. Our download … for us to build a basic database structure and a basic web interface. And we could then show that to collaborators …

… than anyone else.  DAN: Yeah. I mean fine in pandemic adjusted terms right?  MARCY: Yes–  ALISON: Yeah.  MARCY: … But you can carry that idea to bacteria for sure.   On your website and you’ve got some pubs on this. There is at least … It gardens the fungus in order to make parts of it for food.  And then some of our more recent work, what we’ve …

… into practical applications, including sustainable biofuels, biomaterials, natural products, and environmental … to sequence 1000 fungal genomes from across the Fungal Tree of Life, from an international research team in … analysis and genomics data exploration. … The Mycocosm web portal provides data access, visualization, and analysis …

… gold rush. And we’ll talk about a new JGI paper that’s just come out where I got the chance to do genome mining on … bacterial and archaeal orders as seen on the phylogenetic tree, with new lineages of uncultivated genomes from the GEM … Some reviews of genome mining: Ziemert, Alanjary, and Weber’s 2016 overview of genome mining (open access) The …

… can always find at naturalprodcast.com or through the JGI website at jgi.doe.gov . There’s a lot more to talk about … out for sequencing. BRIAN BACHMANN: That’s right. And then just– and then in terms of there’s sequencing an organism by … what we did, we didn’t even sequence the whole genome. We just did a low-resolution shotgun pass where we sequenced …

… microbial ecosystems.  The Program also aims to build a global-scale catalog of viral, microbial, and microeukaryote … have expanded viral diversity knowledge, enabling global exploration. We develop computational tools for … SAGs, MAGs, metagenomes and metatranscriptomes. … GOLD is a web resource for comprehensive access to information …

… company that recycles carbon emissions to make fuels and chemicals, improving air quality and promoting a … engineer a Clostridium strain for the production of biofuels and bioproducts from low-cost gas feedstock. For more …

… of entire chromosomes, advancing the development of biofuels, biochemicals and other bioenergy solutions.  The … focusing on developing genetic systems that can address global energy and environmental challenges. The program … of life, in a uniquely integrated context.  … The MycoCosm web portal provides data access, visualization, and analysis …

We could unlock new innovations to drive more productive food, medicine, and bioenergy crops. But most available genomes are from narrow swaths of the plant tree of life. One project aims to change that. …

TAKEMURA: I wanted to ask, did scientists at that time just think that the ocean was kind of like a desert? Or that … marine life, there were fishes, coral, et cetera, but they just didn’t make interesting chemistry? It seems hard to … and all these kinds of techniques. But the ocean was just not considered to be of any significance. And you know, …

The US Department of Energy’s favorite tree is poplar. They’re the fastest growing trees in the Northern Hemisphere, making them tantalizing …