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… As a host, and a little bit of my newer work is focused on plants, but in both cases, you know, these molecules are how … antibiotics that people were looking for in the soil kept getting found over and over again. So we call this the … this and deal with it is through these antibiotic- or antifungal-producing bacteria that live on the exoskeleton of …

… drive innovations that cross the boundaries of the Plant, Fungal, Algal, Microbial, Metagenome, Metabolomics, …

… Elucidating Sphagnum microbiome genetic interactions for improved growth at elevated temperatures … to soil carbon storage during simulated range shifts of plant-fungal symbionts … the gene regulatory networks governing terpenoid-mediated plant environment interactions to enable advanced bioenergy …

… And I think also the quality that we provide. So for fungal and for a lot of our eukaryotic genomes, all our eukaryotic genomes. Fungal plant, algal genomes, a lot of effort goes into generating … the case. You’re not going to have a greater chance of getting approved because you requested only 100 kb versus …

… where I was a graduate student. Aflatoxin, of course, is a fungal natural product which is a liver toxin when humans … the sponges talk to each other? ERIC:   He was looking at interactions between sponges and other organisms. So one of … transcriptomics, metabolomics, and natural products in plants, fungi, and microorganisms. If you want to …

… estimated 2–6 million species — dwarfing the diversity of plants. To put this evolutionary timescale in perspective, … fungi remain largely mysterious. Only about 200,000 fungal species have been named. Among those sequenced, … genomic analysis due to their compact genomes. While plant and animal genomes can sprawl across billions of DNA …

… that. But it was really fun working together with Kai and getting this thing off the ground. Two fanatic PhD students. … called “disease suppression”, where the microbiome of a plant, so the bacteria living on and inside the roots are protecting the plants against pathogens. So usually fungal or oomycete pathogens. In this case they worked on a …

… merge the chemical synthesis with some of the biosynthesis, getting to get the best of both worlds because I feel like … of biosynthetic gene clusters? DAN: And I don't want to jump on your SIMB talk too-- and I don't-- actually, I … students, we obviously can't put any antibiotics or antifungals in there. So they get just a smattering. JACKIE: …

… of these changes may require new signed paperwork, and getting new documents in place early will prevent disruption …

… ecosystems.  By studying microbial communities and their interactions, the Program aims to unlock the fundamental … sequencing of microbial communities to uncover the complex interactions and functions that shape ecosystems. By … understanding of microbial community assembly and microbial interactions, including microbe-microbe and virus-microbe …

… Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a … nutrients from decaying organic matter (saprobes), and many plant pathogens known to infect most major food crops and … clusters showed a >95 % accuracy in correctly predicting plant pathogens (blue) vs saprobes (green). (From Haridas S …

… us a little intro into just what sparked your interest in getting into natural products. DAN: Why are you here at … intersection of chemistry and biology. And it actually was jumping onto the I ntegrated Microbial Genomes and … DAN: Almost like you know that there is. AARON PURI: It’s a planted question Dan. Yeah. So overall I think what we’re …