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… oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … that you can turn on the natural product, say clusters or expression systems so that-- BETSY PARKINSON: Exactly. DAN: … students, we obviously can't put any antibiotics or antifungals in there. So they get just a smattering. JACKIE: …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges funding from a National Defense Science and Engineering Graduate …

… bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to identify new divergent lineages and expand … complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… Uncovering associations between plant roots and fungi that can help … other plant-associated fungi. Their analysis identified fungal gene families that help determine if these fungi act as … The sequencing project was funded by the U.S. Department of Energy (DOE) Joint Genome Institute, a DOE Office of Science User Facility, …

… is convened by the JGI Director to provide guidance on the Institute’s strategic, scientific, technical, informatics, management, and operational objectives. Serving … the DNA Synthesis Science User Advisory Committee, the Fungal and Algal Program User Advisory Committee, the …

… As an Integrative Genome Science User Facility, the JGI plays a leadership role in providing genome science capabilities to support BER's … drive innovations that cross the boundaries of the Plant, Fungal, Algal, Microbial, Metagenome, Metabolomics, …

… Dr. Grigoriev joined the JGI in 2003, following his postdoctoral training at … the pharmaceutical industry. He holds joint appointments as Fungal and Algal Program Head at the JGI, a Senior Scientist … from protists to plants. In 2009, he launched the JGI Fungal Genomics program which resulted in over 2500 fungal …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … technology to help access complicated natural product gene clusters, and we’re all really excited about that, and … natural products of microbial origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the …

… The JGI’s data stewardship expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, … critical requirements for amplifying the JGI’s impact. Data generated from a single investment will be reused for …

… view of plant evolution and adaptation.    Understanding how genes are regulated is like deciphering the complex wiring … — and integrated these data with single-cell gene expression maps. Together, the scale of data enabled by … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User …

… UDWARY: It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for … I think for Natural Prodcast, I think the question that generally comes up that people come to me asking like is– … And I think also the quality that we provide. So for fungal and for a lot of our eukaryotic genomes, all our …