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… to no genetic tools enabling heterologous expression and functional exploration.  The developed strains represent an …

… a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential … of host-virus interactions, the exploration of the functional dark matter as well as the development of novel … of big data. … Pavlopoulos GA et al. (2023) Unraveling the functional dark matter through global metagenomics. Nature . …

… support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, … and assembling physical DNA constructs that can then be functionally characterized.    We provide custom DNA …

… focused on the application of  function-driven single-cell genomics . Here, single cells are characterized and selected as based on a specific functional trait or phenotype of interest, prior to and in … Chris Rinke: Research Officer, Australian Centre for Ecogenomics Patrick Schwientek: Cofounder & CTO, Oralta … …

… interesting. ALISON NARAYAN: It is a result that has a functional benefit for us, being chemists working with … that in and make that a solid retrosynthetic design. Also functionally, the supply of enzymes. Right? DAN UDWARY: … the future to figure out how to make predictions about the functionality and chemical capabilities of enzymes. Also, …

… are influenced by microbial partners. We use a variety of genomics-powered tools to study this complexity, including … barcode-based genetics (RB-TnSeq), and computational genomics to better understand the plant-associated …

…  Through this identification, metabolomics enables functional genome annotation, improves understanding of the …

… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science The … cells. The fungus is almost always found among and within poplar trees, and in an effort to understand its influence … how poplar responds to its intimate associations with endophytes — a group whose effects on plants are still not …

Nature . The mushroom has a symbiotic relationship with the poplar, a JGI Flagship Genome and the first tree to have its … … Laccaria bicolor has a symbiotic relationship with poplar … Fungal Datasets … Genome Inside: THE Bioenergy Tree …

… it’s really about what are they doing. And so it’s really functional genomics. And there’s a lot of sequencing based approaches, … , like metabolomics , like some of the more directed genomics approaches, DAPseq and the stabilized isotope …

… and protein folding models, to improve the accuracy of functional predictions and speed up genome analysis. … on Phytozome … Phytozome is the JGI's Plant Comparative Genomics portal. Families of related genes representing the …

…   Each year, the JGI accepts proposals for state-of-the-art functional genomics research from reseachers who translate genomic … information into biological function. Through our CSP Functional Genomics call , we look for projects that will …