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… right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … worked out that you could get a precursor of it from the needles and then do a “semi-synthesis”. So, you take a … the mentality that I’m looking at it with, you know, it’s within a species or microbial population, you have some set …

… development of complex biomolecules — which can include antimicrobial and anti-pest compounds.  The program is working … and function. These species are carefully selected by the community to evenly sample the diversity of the plant … quality graphics and explore pangenome views of genes within and across species.  … HipMer is a high-performance …

… as a new type of medicine that will open up a new year for targeted anti cancer drug discovery. DAN: Yeah, great. Are … not only I say we were able to make use of it, but also the community can benefit from the technology. But even better, … genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural …

… parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … of viral infections. The Viral Genomics Group is hosted within the Environmental Genomics group . Research Team … …

… to predict or just understand better the language of microbial cell-cell communication. And he told us about his … covalently attach through a more permanent bond with their target. And so, for example, you could think of designing … a group of genes into maybe the “easiest” organism to grow within that same genus. And so that’s what we’re trying to …

… to see about it is that we talk about conserve between or within a particular genomic lineage. So there is no doubt … can lead to a particular high activity towards a particular target. That’s why an antibiotic has to be a particular … UGA-Langebio in Irapuato, Mexico. His interests are in microbial diversity and evolution, particularly as how …

A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell . 184(13):3376-3393 Almeida A, et … colitis reveals a disease-associated bacteriophage community.  Nat Microbiol. 3(9):1023-1031 Harrington LB et … et al. (2016) Microbiome Data Science: Understanding Our Microbial Planet. Trends Microbiol. 24(6):425-7. …

JGI User Executive Committee (UEC) represents the JGI user community and is responsible for providing input and advice … user meeting. The UEC also acts as a liaison to the user community and the broader scientific community and promotes communication and collaboration within the user community. UEC responsibilities include: …

… today who I have a very personal connection to. So our “target” today is Eric Schmidt, who’s a professor at the … How’s it going, Eric?  ERIC:  Good. It’s an honor to be targeted by you, Dan. DAN: I’m not quite sure where to start … do you think it was about that? What factors led to the community – not necessarily competing, but – sort of, diving …

… exposing that extract to something that you want to try to target. So if you’re trying to find an antibiotic, then you … an activator, to go ahead and, and synthesize those genes within a model organism like E.coli , and have it produce … thrust that we’re interested in doing. So we need the community.  And one of the other great things about …

… below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, as well as … genetic microdiversity or core metabolic flexibility? … Microbial contributions to soil carbon storage during …

… of those pathways come from bacteria that actually live within, say, the sponges or other things. And we know lots … to be a problem. Many of these molecules, too, hit the same target. And so there’s always a need to find new antibiotics that hit new targets because if you haven’t – So resistance comes about …