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… DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m … chemical biology, a lot of which people classify as tool building. So I worked with a really great guy named … And it actually was jumping onto the I ntegrated Microbial Genomes and Metagenomes, the IMG platform that JGI has that …

… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples … of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is … and delays on the work. The transfer of a proposal from one commercial institution to a new commercial …

… help with: preparing a Statement of Work, completing a formal User Agreement, and ultimately launching the user’s project. See below for details on each step. … Before work can start on any approved proposal – including the … that all work performed in its User Facilities be covered by the User Agreement. …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided for all sequencing products below. In addition, JGI will … Program leads to discuss available options. Note: In 2021, we conducted an extensive internal product audit to …

… I think it must’ve been about 2001, maybe, and so it was before smartphones and before laptops and everything. And I … that I’ve appreciated since starting my own group is these tools, in terms of looking at the chemistry produced by … we might play on air, email us at JGI-comms. That’s JGI dash C-O-M-M-S @ lbl.gov . And, because we’re a user …

… An assay used for profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … samples in 96-well plates on automated liquid handler platforms, substantially increasing efficiency and scalability. … The pipeline utilizes internal analytical standards to accurately measure environmental microbiome activity levels. …

… Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … the Nature Chemical Biology — or early this year– this new tool that we call CORASON, which is basically an acronym to … we might play on air, email us at JGI-comms. That’s JGI dash C-O-M-M-S @lbl.gov. And, because we’re a user facility, …

… DAN UDWARY: Hey, everyone. I’ve got a great episode for you here today. We got the opportunity to talk to one of … for culturing, and then of course using modern phylogenetic tools measuring genes, the 16S gene, and comparing it with … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … is a bacterial sacred metabolite, and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, … so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. You know, we have this …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … and SIO. Oh, I should say what those are. Brad: What’s SIO, for all those listeners out there? Dan: Scripps Institution … us is connecting genes to chemistry to really expand the toolbox of biocatalysts that we work with. Seemed like …

… insights into environmental tendencies The Science The  Metagenome Stability Diagram — a tool within the Integrated Microbial Genomes and Microbiomes (IMG/M) platform — has been developed to help inform scientists and … The work conducted by the US Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE Office …

… Dan Udwary: Hey everybody! Welcome back for Natural Prodcast episode 17. The guest we have this week … get a DNA sequence first. And there are plenty of software tools to find natural product gene clusters, and even be … we might play on air, email us at JGI-comms. That’s JGI dash C-O-M-M-S @ lbl.gov . And, because we’re a user …