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… pathways, which led her to a successfully funded JGI CSP project. And we also got to talk about work at her … And so we've been really interested in trying to find new hormones that can activate receptors and clusters that … coelicolor versus Streptomyces lividans. They both have the genes. The genes are pretty much 100% identical. We don't …

… and their roles in the environment, can unlock new avenues for bio-based products and bioenergy crop … the program strives to facilitate the discovery of new bio-based molecules that can drive innovations in … the data. It is also a place where the community can upload new data for use by scientists and the public, and provide …

… e01280-22. 10.1128/msystems.01280-22 Clum, A. et al. (2021)  DOE JGI metagenome workflow …

Reach the next generation of genome scientists and recruit new talent for biosciences.  Adopt-a-Genome has:  11 CSU …

… schedule for a while. Moving forward, I’m hoping to get a new one out every two weeks. This time, we’ve got a great … third international meeting on natural products, but as a new, I call it “incarnation”, for this series of meetings. … and we have this, called antibody drug conjugates, as a new type of medicine that will open up a new year for …

… technical input on large-scale production sequencing, new sequencing technologies, and related informatics; … at the JGI; and overview of the Community Science Program (CSP). A crucial job of the committee is to take the input from the CSP Proposal Study Panel on prioritization of CSP projects …

… that genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the … work. And that it involves some of these crazy genes, some of these enormous genes that encode these very … interesting biosynthetic gene clusters in there to find new antibiotics. And, as many projects in bioinformatics, …

… this conversation about 10 months ago. I was pretty green at the time and had some really tedious technical … have a better understanding of what is what. This is not new. It actually was first proposed by two authors called … the regulation off, rather than negatively get rid of the genes from their genome. FRANCISCO BARONA-GOMEZ: Exactly …

… in how the community itself works together to elicit new metabolite production. And we are also interested in how … Do you think that they always cluster or could the genes be separated on a genome?  Dan: Oh yeah. It’s biology … on increasing computational skills among biologists JGI CSP Proposal: Metagenomic mining of natural product …

Program leads to discuss available options. Note: In 2021, we conducted an extensive internal product audit to … Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, cloned into … Constructs 5-10kb in size Single gene or multiple small genes assembled totaling 5-10kb in length, cloned into …

… approved through the annual  Community Science Program (CSP) call of the U.S. Department of Energy (DOE) Joint … white paper focused on duckweed through the  CSP New Investigator call . It is the first project to have … now a facet of the  Fungal & Algal Program . For example, green algae represent the largest group of primary producers …

… moved there in the early ’60s from Berkeley to work on this new budding field of marine natural products. And was at the … JGI projects over the years starting with, you know, the CSP that we did and then leading up to today to some … And perhaps using biocatalysts we can do it in a cleaner, greener way. That’s one of our motivations, as well. Alison: …