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… a recent Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the watersheds … a community-science program to collect samples from across the country to standardize the process. They noted … Researchers catalog the microbiome of U.S. rivers …

… tell us about this squid-microbe relationship. Or is it a microbial community with microbial community relationship?  … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … they don’t transfer a lot of DNA back and forth, especially across species. And so then there isn’t horizontal transfer …

… and a tool for predicting natural product structures from genomes. And I was writing grants furiously to try to get … Did the global analysis of biosynthetic gene clusters across, well, at that time, all genomes that were out there. … IMG kind of hooks into IMG’s data. IMG being Integrated Microbial Genomics at JGI, a large data set of bacterial …

… in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to … relationships and to provide valuable reference genomes in under-populated areas of the tree of life, as …

… a User Facility means that scientists from all over the world bring us big problems related to energy and the … right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … be so mind bending and that we might just kind of happen across them in our food. That’s crazy!  DAN: Yeah, just like …

… we’re all really excited about that, and I think that comes across in the interview. If you listened to the Primer … well. One is to do DNA sequencing. So upon sequencing many genomes, now we don’t have to, as in the past, go randomly … genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural …

… exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With … systems can provide novel insights into the impact of microbial symbionts and their hosts on ecosystems.   … demystify the complexity of dissolved organic matter (DOM) across a variety of environments. ENVnet allows us to …

… Dan. DAN UDWARY: So we’re back in our far corners of the world. So, yeah. ALISON TAKEMURA: That’s right. Yeah, we’re … yes, sure, right. And yeah, so we worked on the Salinospora genomes. That was a really fun project. We had Brad on and … she was leading this team effort to sequence microbiomes of rivers around the world and that JGI was being very helpful …

… on an accelerated timeline as compared with the standard CSP projects. In addition, they must utilize a broad range of the capabilities across at least two of the facilities, and generate datasets … samples of the spatial, temporal, taxonomic (environmental, microbial, plants, invertebrate, and vertebrate), and …

… So yeah, in terms of, I guess, fields of science, we span across them. But fundamental is the chemistry produced by … there have been huge advances in both. The cool thing about genomes is you can, well, if your assembly is good, you can … And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is …

… Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, … of transcription factors and determine their binding sites across multiple genomes. Computational prediction of heterologous … for secondary metabolite biosynthetic gene clusters (BGCs) across all kingdoms of life. Tools are provided to display …

…   Our Sequencing Technologies Group is well-integrated across JGI departments to ensure a robust offering of … assay used for profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …