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… and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, archaea, they all have … products because they’re easy to find. They grow in the soil. These are the same guys that produce geosmin. And so … natural environment. They usually grow down within the soil. And that purple blob is going to be chock full of …
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As a host, and a little bit of my newer work is focused on plants, but in both cases, you know, these molecules are how … for antibiotics and the microbes that make them is in the soil. There’s … uh… there’s an issue there though, in that … few of the antibiotics that people were looking for in the soil kept getting found over and over again. So we call this …
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… contigs. Assembly, annotation ( IMG ) Depends on project Plant and Algal Standard Draft Whole genome shotgun … these projects. Assembly, annotation for ( Phytozome for plant, Phycocosm for algae) depends on genome Plant and Algal Resequencing SNP and short indel calls, …
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Uncovering associations between plant roots and fungi that can help or harm plant host health. The Science Researchers compared the … Arabidopsis thaliana roots with genomes from other plant-associated fungi. Their analysis identified fungal gene …
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Yeast recombination and Golden Gate methods SynTrack and associated tools, which track samples through the JGI’s …
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… the special, natural chemical compounds that you find in plants, fungi and bacteria, basically all living things. … is a chemical compound called geosmin that’s produced by soil bacteria that live all over the place. So that smell of … secondary metabolism. ALISON: Right sort of outside of the core that’s central for living organisms. DAN: Right, all of …
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… of these environments? NADINE ZIEMERT: So we started with soil. But we also have, in collaboration with other people, … all the time. We have compared three very different soils in the area around Tübingen that is almost next to … transcriptomics, metabolomics, and natural products in plants, fungi, and microorganisms. If you want to …
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… with a contract manufacturer to actually have them build a plant for production and fermentation and transfer that … risks that would lead to things like leakage of organism, plant, product, et cetera. But yeah, I think it allowed us … DAN: Correct. NIGEL MOUNCEY: But they really span our core science programs which are microbes, and fungi, and …
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… transcriptomics, metabolomics, and natural products in plants, fungi, and microorganisms. If you want to …
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… ag[riculture] and I really liked – I became interested in plant disease in part because of what happened in my Peace … or natural product called T-toxin. And this kills corn plants. So I became very interested in toxins – phytotoxins … was the natural product he was talking about. It was associated possibly with esophogeal cancer or a neurological …
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… or online catalog, I guess. So we've also been able to get soils from Purdue campus itself and been able to actually … have several undergrads from the lab go out and get soil from different areas around their dorm and things like … all other kind of examples that have gene clusters with associated molecules that have these [penicillin binding …
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