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… begin work, checking such factors as genome size, polymorphism level, sample quality and availability, etc.   During … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on … the completion of a project, the JGI makes the assemblies, gene annotations, and analyses available to the community at …

… the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … other compounds that are produced, and we don’t know what potentially other targets, if there are actually other … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… and the science and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. … more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … ALISON TAKEMURA: I know that it’s looking in the genome for genetic elements of interest, you know, something like …

… capabilities support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, …

… technology to help access complicated natural product gene clusters, and we’re all really excited about that, and … and enabling technology, but interesting biology and a potential application of translation in medicine. So it’s a … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

Science One of the most vital pieces of equipment for fly fishing is a boxful of lures. Designed with feathers or … of microbial enzymes, which could have a plethora of potential applications to industrial processes. Summary JGI … cell sorting to sort cells into several small pools, followed by whole genome amplification and …

Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … exploring how to convert sequence into functional assessments. The team has a research & development group, a team …

… my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … products work, right? Think about how many things that are potential drug molecules that have micromolar activities. … to some people more about down the road. Email Nigel! He’ll sequence whatever you want!  [LAUGHTER]  NIGEL MOUNCEY: We …

… association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … part of that, the monooxygenases, has to do with the mechanism. And so these enzymes use O2, and one of those oxygen … could have arisen from. DAN UDWARY: OK, so sort of a phylogenetic reconstruction kind of a thing. ALISON NARAYAN: …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … and 200 polar/500 nonpolar metabolomics samples, and should generally conform to the guidelines for our  CSP Large Scale … and personnel resources for genomic research and sequence-based science.  Projects include de novo generation …

… of microbial communities based on their metagenome sequence, in the context of reference isolate genomes … rich data such as inferred host taxonomy, conjugation potential, antibiotic resistance genes, and ecosystem information. … The IMG/VR database …

… of certain types of data to support their use by those generating data. The JGI Data Policy applies to research … on relevant JGI portals (i.e. JGI Genome/Data Portal, MycoCosm, PhycoCosom, Phytozome, or IMG) and outside repositories … embargo starting at construct or strain delivery.  Detailed sequence information for constructs are made publicly …