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… those two groups and the ways in which they approached scientific problems. And so that sort of opened my eyes to the … and that there might be more to be gained than just subject matter, by making that change. So I went to the University … a sort of evolving trajectory. I think, you know, most scientific careers are like that, in that they they follow an …

… data that the JGI produces to try to find and identify natural product biosynthetic gene clusters and to do … a review of Natural Prodcast on Apple podcasts, Google, Spotify, or wherever you got the podcast. If you have a … products. You can find the podcast on Apple , Google , Spotify , Stitcher , directly with the RSS link , and via most …

… and did some meta-T [meta-transcriptomics] on that and identified just a small subset of transcripts up-regulated … cool because the work has gone so much more than just identifying genes to that toxin, but it’s opened up this whole … then the organisms all around us or the, you know, the bio matter that’s around us now? Brad: Yeah, I mean, petroleum …

… things that he worked on was he worked on how very beautiful sea slugs that eat sponges concentrate those toxic … And so we’ve been working on that. But why small molecules matter is because this pain drug, this peptide that’s used, … evidence was very indirect at that time. And why does that matter? It matters because there are a lot of potential …

… in microbiome data science. … National Energy Research Scientific Computing Center … DOE System Biology Knowledgebase … …

… about what kinds of proteins exist in a cell and identify those proteins that are enzymes that are doing the … there. So once you could sequence DNA, then it was just a matter of time before some secondary metabolism gets … genes are found clustered in the DNA. And so if you can identify a gene that’s likely to be involved in secondary …

… their strains for sequencing, as long as they have a scientific question that is relevant to DOE missions.  Learn more … scientists who are seeking to build upon their line of scientific inquiry by leveraging JGI experimental, computational …