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… and we talk about an ongoing project I’ve been working with him on as an exploration into the secondary metabolism … started looking at things and doing chemical structures, learning a little bit about things. And that was the … so about the same time– this was around 1990– we made some discoveries that really looked promising. We found that …

… kinds of biology, one of the best things that we do is work with this really great group of biologists that know what … to get towards that.  Organic chemistry doesn’t really help with getting to something other than the sort of really … noise from the metabolomics data. We’ve done a lot of work learning about how to use statistical analysis to prioritize …

… applications will focus on high-risk/high-payoff proposals within the focused topic areas that can be completed on an accelerated timeline as compared with the standard CSP projects. In addition, they must … of funds. All data is made publicly available in accordance with  JGI’s Data Policy . In cases where the JGI provides …

… clones if low number of variants, or pool of variants with sample sequencing to predict the number of successful … Used for the identification of active groups of organisms within a community. Individual samples are fractionated …

… to a regular schedule. I’m going to kick things off today with my interview with the Director of the Joint Genome … firstly set up a baseline process. And then really dig deeper into both aspects of the strain, as well as the … we’ve done a lot on our spinosyns. We had a huge amount of learnings to apply to this second product, the UK2A base …

… in making this happen. We had a really fun conversation with Roger about all this, in terms of how to build an … It was designed to ensure equitable benefit sharing if any discoveries were made that were of value to the host … for Ray Andersen there, and had a very enjoyable time learning about natural products science. DAN:  Yeah, great. …

… because I really enjoyed the review that you wrote with Marnix on putting that stuff together. It’s been kind … putting things, coalescing them, so that we can really make discoveries. And so I’m really excited to have read that … went for it. And it was fascinating. And I fell in love with actinomycetes. I loved approaching biology from a …

… been a pioneering effort in functional genomics since 2012, with a focus on addressing critical energy and environmental … and biosystems. It The program fosters collaboration with U.S. and international scientists to drive innovations that align with DOE's missions. …

… 8 of Natural Prodcast. This week, we have our conversation with Professor Eric Schmidt, from the University of Utah. … challenges that usually lead to surprises and really great discoveries! And Eric’s done an awesome job, in that … peptides”. And, you know, we don’t need to get too deep into the chemistry but let’s talk about that compound …

… week is Professor Cassandra Quave from Emory University, with joint appointments in the School of Medicine and … being just so incredibly important to advancing these discoveries. The idea that something can go literally from … I think could be leveraged better could be perhaps to take deeper looks at the interactions that organisms have, not …

… a new login service, requiring the use of an ORCID account with two-factor authentication enabled to log in. Check our … over 15 million viral genomes and fragments, enriched with functional annotation, taxonomic classification, and … The JGI Genome Portal was replaced with the Data Portal and sunset in 2026. The Genome Portal …

… Metabolism Collaboratory data portal I’ve been working on with my colleagues Drew Doering and Bryce Foster and too … different disciplines. And so then going to grad school and learning about chemical biology, which I don’t think it was … back in the ’50s and ’60s of the golden age of antibiotic discoveries. Everything that we’re finding seems to be a new …