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… pairs. It was not linear, like Streptomyces , but circular. 10% of the genome encoded natural product pathways. Dan: … Brad: Yeah, at that time, that was new, right? Like, my god 10% of the genome makes small molecules that have, you know, … of changed over the years. And I think maybe over the last 10 years, I’ve really become a fan of having postdocs, and …

… first started out the natural product community was almost 100% bacterial. Only people working in mycotoxins worked … mostly coming out of China and India, very cheap for $100-$200. But you have so many contigs. This is a problem … Basidiomyetes might get to 50. Some of them go to over 100. There. That can be the problem. Whereas the bacteria, …

… is already the most comprehensive BGC database available at 10X the scale of the closest comparable database, and has … of Energy Joint Genome Institute (https:// ror.org/04xm1d337), a DOE Office of Science User Facility, is … of Science of the U.S. Department of Energy [DE-AC02-05CH11231]. …

… proposals as well. I’ve been at the JGI for 20 years, and 10 of those years, I’ve been a project manager. MENAKA … amount that they can request. So the minimum request is 100 kb. The maximum request is 500 kb. DAN UDWARY: For DNA … chance of getting approved because you requested only 100 kb versus 500 kb. In the lab, they’re going to do the …

… pathogenesis . Science. 2006 Sep 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …

… 179% 2,208 2,064 95.4% Q2 2026 175 243.806 139% 2,160 2,112 99.8% Q3 2026 175     2,164     Q4 2026 175     2,208     … % Goal   FY 2025 Total   700.0 1,144.186 163% 8,585 8,640 100.6% Q1 2025 175 190.304 109% 2,164 2,136 98.7% Q2 2025 175 152.100 87% 2,117 …

… the number was. But I want to say it was like less than 10. Since, you know, a recent decade.  DAN: I’m sure that’s … to check her stat and she was absolutely correct. Since 2010 there have been eight new antibiotics added to the … C, and you’ve got a new molecule, right? And so if you have 1000 A’s and 1000 B’s and 1000 C’s, then if you’ve got a …