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Benjamin Cole
… was primarily on how plants interpret different light cues by altering their growth program, and on how plants … In addition, Dr. Cole is focusing on how individual plant cells respond to their biotic environment using emerging single-cell characterization technologies (scRNA-seq, Spatial …
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Expanding Virophage Diversity
Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages are small viruses … genome sequences 10-fold through computational approaches. By mining more than 14,000 publicly available metagenomic …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… the stars in the Milky Way, viruses outnumber the microbes by at least another order of magnitude. For years, … workflows that allow researchers to easily analyze viral genomes. This includes (i) classifying viruses into groups … the quality and completeness of metagenome-assembled viral genomes ( Nature Biotechnology , 2021), geNomad , a tool for …
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David Goodstein
… extensive structural mutation in the laboratory. The Plant Cell 35 (2), 644-672 A Sreedasyam et al., 2023. JGI Plant … of interest and gene copy number variation across multiple genomes.  eLife 11, e78526. Li et al., 2021.  Plant … et al., 2020.  Gradual polyploid genome evolution revealed by pan-genomic analysis of Brachypodium hybridum and its …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
However, genome and metagenomic sequencing conducted by the U.S. Department of Energy Joint Genome Institute, a … for the bacteria to orient and swim than they would gain by pursuing nutrients and other resources in the open … Other surprises in the research include a similar loss of cell walls and a complex pattern of evolution for genes …
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Honey Bee Gut Microbiota Divvy Up Dinner
… absorbable solution of sugars. But pollen contains plant cell walls, which have complex, branching chains of polysaccharides called pectin and hemicellulose. While these two polysaccharides can yield sugar … that pollen’s pectin and hemicellulose are degraded mainly by just two clades:  Gilliamella,  which mostly resides in …
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Taking Stock of the Known and Unknown Microbial Space
… technologies have led to an abundance of microbial genomes becoming available to the global research … a deep dive into over 1.8 million bacterial and archaeal genomes to see how much of their diversity we've actually … of the available datasets. Efforts to recover MAGs by extracting data directly from environmental samples over …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… are everywhere — in soil, the sea and, of course, the cells of other organisms. As they infect microbes like … Beginning in the early 2000s , these environmental metagenomes began to offer a window into viral existence. Along … That study multiplied the number of known viral genes by a factor of 16. The same year, the JGI expanded its …
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JGI announces 2024 Functional Genomics awardees
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Pinning Down a Piece of Photosynthesis
By studying the structure and function of a cyanobacterial … no one’s ever had a structure of before,” said Crysten Blaby-Haas, a research scientist at the JGI and Molecular … structure of the protein related to its function inside the cell, Grosjean used the JGI-developed  guideRNA and Sequence …
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Contribution of calcium ligands in substrate binding and product release in the Acetovibrio thermocellus glycoside hydrolase family 9 cellulase CelR
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Better Crops With a Pointillist Approach to Plant Genomics
In this episode, we peer into plant cells. Researchers are using measurements from single cells to understand which genes help plants grow, get …
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