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Strain Engineering
… project types, in which DNA-based molecules can be chromosomally integrated into a taxonomically diverse suite of …
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Zhong Wang
… data analyses and software to enable “grand-scale” scientific projects. These solutions include large-scale … in the coming years the Wang group will continue its effort to explore new genome and computational … metagenome binning software … Education … Selected Publications … Software …
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JGI-KBase Panel at SACNAS
Nov. 2: Getting Credit for Scientific Contributions of Any Size … contributions using the Contributor Roles Taxonomy and what sorts of platforms researchers use to manage their …
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Extracting the Secrets of Secondary Metabolites
… is the leading tool for accurately editing genomes, its effectiveness has historically been limited due to the … agriculture, and other industries — yet there’s still so much about them we don’t know.  Unlocking the power of … CRISPR into other bacteria, thereby enhancing the scientific community’s understanding of how secondary …
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Jeremy Schmutz
… working for the Stanford Human Genome Center, now the HudsonAlpha Institute for Biotechnology. There he constructed … and DOE relevant cellulosic feedstocks. Schmutz provides scientific project management for the reference eukaryotic … Award … Plant Science Program … Education … Selected Publications … Awards and Honors …
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The More the Merrier: Making the Case for Plant Pan-genomes
… genome copies from additional parents or duplication, also known as “polyploidy,” is common among flowering plants; … fruit and flower size, and confer stress tolerance traits. Given the importance of polyploidy in plants, … and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s Office of …
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Genome‐wide association studies and expression‐based quantitative trait loci analyses reveal roles of HCT2 in caffeoylquinic acid biosynthesis and its regulation by defense‐responsive transcription factors in Populus
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Olpidium, The Key to the Origin of Terrestrial Fungi
… lab describes the effort that led to the work published in Scientific Reports . Before 2006, Olpidium was one of the … of some common crops, such as lettuce and tobacco. Olpidium itself doesn’t cause much damage to the hosts, but they are … attracted the attention of many mycologists with the two publications of the kingdom-wide, multi-gene phylogeny of …
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Enlarging Windows into Understanding Gene Functions
… revealing how genetic variations in sequences affect traits. In a text file, the rows of letters A, T, C and G … of a streamlined workflow that reduces the time and cost associated with this purification step, and Baumgart continued … and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s Office of …
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The Megadata of Lake Mendota - Part 2: Souped Up Computing
… assembly from Wisconsin’s Lake Mendota. In this episode: a look at the supercomputing that stitches together … large datasets with the assembler program MetaHipMer2. Oak Ridge National Lab is home to two supercomputers — … of data with MetaHipMer2. And the National Energy Research Scientific Computing (NERSC) has another supercomputer, …
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A One-Stop Shop for Analyzing Algal Genomes
PhycoCosm is one of the largest data repositories of its kind, with an interactive browser that allows algal … They play key roles in global carbon cycling, are sources of natural products, and have potential as biofuel … PhycoCosm has many components that make it useful for scientific inquiry: it shows a full phylogenetic tree of …
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Better Living Through Bioenergy
… are a way to kick our addiction to fossil fuels. In this episode, we peek into how scientists Aindrila Mukhopadhyay and …
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