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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… applying them to environmental and energy challenges. But not all scientists have the expertise and resources to do … a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab), comes in. The … more than 10 papers, including two Nature Plants publications, in five years, have come out of the …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
Ancient  Chloroflexota s ditched their flagella and other … found there utilize a unique array of chemicals not typically found in oceans or soils.  A recent study … in pesticides and refrigerants. Researchers found a number of surprising traits in  Dehalococcoidia inhabiting hot …
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Gut Fungi: Unexpected Source of Novel Chemicals
… from herbivore poop make surprisingly complex compounds — an energetically expensive feat thought to be too costly for them. The Science Anaerobic fungi, which … of natural products. In the lab, O’Malley and her team — notably, first author Candice Swift — verified that the …
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JGI@25: Studying Sorghum’s Survival Skills
… the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have …
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Tracking the Origins of Methane-Producing Microbes
Mini-Metagenomics Approach Helps Identify Novel Archaeal Methane Metabolism. Methane-producing archaea are estimated to … hydrogen-dependent and CO2-reducing, or hydrogenotrophic (most common); methylotrophic; and, acetoclastic. … , researchers at Stanford University, the Chan Zuckerberg Biohub, and the U.S. Department of Energy (DOE) Joint …
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The Expanding Universe of Methane Metabolisms in Archaea
… archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 times … representing new potential methanogenic, anaerobic methanotrophic and short-chain alkane-oxidizing archaea. They used IMG because the database already contains metagenome datasets …
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Hiroshi Otani
Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly … Mol. Microbiol. 87, 1223-1236. PubMed … Education … Publications …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
New studies show methanogenesis is not exclusively for Euryarchaeota. Atmospheric … devoid of oxygen and until recently were thought to be the only microorganisms capable of methanogenesis —  it’s …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
Researchers looked across many organisms to see that aminotransferase enzymes have … has a rich back story — they rely on enzymes that have been evolving for billions of years. However, these enzymes …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… to those from fungi when it comes to breaking down tough plant fibers. The Science Walk in a temperate forest filled with … While large protein databases, like UniProt, exist, are not specific enough for a microbial community like that from …
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2024 Progress Report
… the National Microbiome Data Collaborative (NMDC), and Berkeley Lab Biosciences Area are also co-located in the … processed 13,700 metabolomics samples With our users, 247 publications were published   … Our primary objective is to … Science and Operations review of the JGI. This provided not only the chance to speak to our accomplishments of the …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … with the HudsonAlpha Institute for Biotechnology. Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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