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CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  The Science Microbial … its secondary metabolites and their pathways could fuel further agricultural applications for pest control and understanding how the pathogen uses insects for fuel.  The impact of the pairing could prove to be much more …

… releasing fresh organic carbon which can serve as a food source for other microbes into the environment. Summary … Approximately 150 archaeal viruses had been previously identified. The JGI researchers surveyed publicly available data …

… one of the largest carbon sinks in the ocean — occupying just 0.2% of the ocean floor, these meadows are responsible … clock independently provided timepoints of eelgrass’s major global colonization events. The U.S. Department of Energy … — bioinformatics expertise, as well as sequencing for all global populations of eelgrass used in the study to reveal …

… an abundance of microbial genomes becoming available to the global research community.  Published January 17, 2025 in … to multiple research areas including agriculture, biofuels and bioproducts, and medicine. Wading through 30 years … to isolate genome data, our real-world touchstones, we’re just scratching the proverbial Petri dish,” Seshadri said. …

… foundational science, creating opportunities for the global research community. The U.S. Department of Energy … the Changing Planet (download a copy at jointgeno.me/2024StrategicPlan .) This plan aligns the DOE Office of … specialize in doing this at scale, providing our users not just with data, but offering expertise and resources to help …

… the largest analysis of 5mC distribution across the fungal tree of life to date, involving more than 500 species of … 5mC, an important piece of the epigenome. Across the fungal tree of life, they tracked the evolution of 5mC pathways …

… … All proposals will be externally peer-reviewed for scientific merit, DOE mission relevance , proposed data usage by … Tanja Woyke, Deputy for User Programs. Technical and Scientific Leads will also be available to answer any questions …

Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … in the past decade, researchers have uncovered genomes for just a small fraction of Earth’s microbial diversity. … genomes available at that time. “Looking across the tree of life, it’s striking how many uncultivated lineages …

… a login at https://signon.jgi.doe.gov ). Once users are notified that their proposal has been accepted, the PMO will … of Institutional User Agreements Coordinating with JGI scientific and technical experts Project design with Principal … or DOE JGI staff to resolve issues, as needed Users are notified as projects reach specific milestones, either by …

Varga et al (2019) Megaphylogeny resolves global patterns of mushroom evolution. Nature Ecol Evol . … (2018) Leveraging single-cell genomics to expand the fungal tree of life.  Nature Microbiol. 3(12):1417-1428. Haitjema … of the marine picoeukaryotes  Micromonas. Science . 2009; 324: 268-272. Bowler C et al. The  Phaeodactylum genome …

The Community Science Program (CSP) provides the scientific community at large with access to high-throughput … program, the DOE aims to advance genome science-based scientific research from a broad range of disciplines. Three … not require an LOI.  Projects will be chosen based on scientific merit, judged through independent peer review, and …