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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… rely on enzymes that have been evolving for billions of years. However, these enzymes are often loosely understood, … approaches to look at how this enzyme family evolved across 90 species. “One unique thing about this work was our focus … that even enzymes that evolved separately for billions of years have some common signatures of muli-substrate …
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The Expanding Universe of Methane Metabolisms in Archaea
… gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key … metabolisms is “vastly underestimated.” In the March 4, 2019, issue of Nature Microbiology , they mined the Integrated … with the first traces possibly at ~3.5 Gy (billion years),” Borrel and Gribaldo said in an email. “Therefore, …
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A Community Resource for Secondary Metabolite Researchers
… expediting BGC and biosynthesis research.  Summary Over the years several secondary metabolites databases have been made …
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Tracing the Evolution of Shiitake Mushrooms
Lentinula genus diverged roughly 28 million years ago, when the largest mammal ever, Paraceratherium, … samples was a global collaboration that brought together 39 researchers from eight different countries. Genome and … award 0000238431 to D.H., the GENOBIOREF (BIO2017-86559-R) project of the Spanish Ministry of Science and …
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When “The Blob” Made It Hotter Under the Water
United States began forming in Alaska. Over the next two years it slowly spread, raising water temperatures by a few …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
… that adapted to marine environments hundreds of millions of years ago.  The Impact Chloroflexota are bacteria that act … production. … The work (proposal:  https://doi.org/10.46936/10.25585/60000691 , and  https://doi.org/10.46936/10.25585/60007554 ) …
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Ancient Algae Reveal Secrets of Plant Evolution
… that helped plants conquer land over 600 million years ago. The Science By studying the genes of land plants’ … Science Foundation (NSF) CAREER award (DBI-1652164, 1933521), the Nebraska Tobacco Settlement Biomedical Research … States Department of Agriculture (USDA) award (58-8042-9–089), the National Institutes of Health (NIH) awards …
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JGI@25: From Life at the Extremes to Editing Genomes
… to seven. Doudna was recognized for her work on CRISPR-Cas9, technology described by the Nobel Foundation as having “a … impact on the life sciences.” Building upon CRISPR-Cas9 work, the Doudna lab at UC Berkeley seeks other enzymes in the CRISPR-Cas system. For the past few years they have partnered with JGI’s Microbiome Data Science …
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JGI@25: Fueling Investigation into Methane-Making Microbes
… a JGI Community Science Program proposal that started six years earlier, researchers put together what they called the … capable of knocking down human RNA the way that CRISPR-Cas9 systems snip DNA. This could eventually lead to …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… and filtering water. Peat formed there over thousands of years sequesters more carbon than all other vegetation types … protecting these ecosystems. … The work (proposal no. 10.46936/10.25585/60001030) (A.J.S.) conducted by the US …
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JGI@25: Using Team Science to Build Communities Around Data
… represents affiliations at over 180 organizations in 29 U.S. states and 35 countries. (Graphic: Neil Byers) The … co-authors with affiliations at over 180 organizations in 29 U.S. states and 35 countries. Of the 85 proposal … has “significantly advanced our understanding of 1 billion years of evolution in Kingdom Fungi — from phylogenetic …
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Marine Microbe Contains Multitudes
… cruises in 2015 and 2016. At Station ALOHA , site of the 30-years-long Hawaii Ocean Time-series (HOT), they collected … was supported by grants from the Simons Foundation (#329108 and #721223 to EFD) and Gordon and Betty Moore …
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