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Genome‐wide CRISPR‐Cas9 screen reveals a persistent null‐hyphal phenotype that maintains high carotenoid production in Yarrowia lipolytica
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Division of the large and multifunctional glycoside hydrolase family 2: high functional specificity and biochemical assays in the uncharacterized subfamilies
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JGI Announces 2026 Functional Genomics Recipients
… Ritu Singh, Jiaqi Tan, Claire Willing Each year, the Joint Genome Institute (JGI) accepts proposals for … genomic information into biological function. Through our CSP Functional Genomics call , we look for projects that … metabolize and mobilize rare earth elements and other high-value resources. Enabled by the capabilities and …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… work enabled by the JGI’s Community Science Program (CSP) . The Impact Cyclic di-GMP controls microbial … at the University of California, Berkeley and the Joint Genome Institute, a DOE Office of Science User Facility, … biosensor that can produce both large signal changes and high signal intensity for imaging. The work was enabled in …
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Uncovering Novel Genomes from Earth’s Microbiomes
… methods in the past decade, researchers have uncovered genomes for just a small fraction of Earth’s microbial … into KBase has immediate value because people can find the high-quality MAGs and use them to inform future analyses,” said … characterization and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that …
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Emiley Eloe-Fadrosh
… training in human microbiome research at the Institute for Genome Sciences at the University of Maryland School of … Institution of Oceanography. She stepped into the Metagenome Program Lead position in 2017. She also leads the … users with questions on how to partner with the Metagenome Science Program on their research are encouraged to …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… order of magnitude. For years, scientists at the DOE Joint Genome Institute, a DOE Office of Science user facility … Notable examples include CheckV , which assesses the quality and completeness of metagenome-assembled viral … and Data Collaboration Center (CODCC), is led by a team of highly experienced investigators from institutions including …
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Defining a Pan-Genome for Antarctic Archaea
… Analysis of haloarchaeal metagenomes broadens understanding of Antarctic biogeography. … use. Summary Conditions such as extreme cold, high levels of salinity and the sheer distance from other … has been enabled through the JGI Community Science Program (CSP) . Cavicchioli and his team compared two strains of …
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A Collaboration to Improve Plant Genome Annotations Across Species
… keep updating the Gene Atlas with curated datasets from CSP projects and aim to improve plant gene function … plants but not the ammonium. These results highlight differences in plants’ response to nitrate … a subscriber? Avinash: It has been publicly available since 2018. There were more than 15 citations even before this was …
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The Expanding Universe of Methane Metabolisms in Archaea
… Metagenome-assembled archaeal genomes provide new insights into … National Park. This large geothermal pool contains high levels of sulfur, methane, carbon dioxide and hydrogen. … State University, commented that “Washburn Hot Springs is a highly-reduced, suboxic system that may be analogous to …
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Mesophilic and Thermophilic Conditions Select for Unique but Highly Parallel Microbial Communities to Perform Carboxylate Platform Biomass Conversion
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LmbE proteins from Bacillus cereus are de‐N‐acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis
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