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… intensive. This is often due to, for example, tight regulation of biosynthetic gene clusters (BGCs) in native hosts, the complexity of …

… Accepted proposals emphasize JGI interests in algae and secondary metabolites. A total of 27 proposals … and then use computational tools to analyze biosynthetic gene clusters and then develop them for a range of … algae represent the largest group of primary producers generating organic compounds through photosynthesis, but …

… where he developed novel tools for large-scale in situ gene expression analysis in multicellular organisms. During … and experimental sequence-based methods for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of thousands of genetic switches implicated in developmental and disease …

… the “DOE Tree,” poplar is considered one of the  Flagship Plants for the U.S. Department of Energy (DOE) Joint Genome … molecules that combat infections. When the  PtrbHLH011 gene was knocked out in poplar, those plants produced double … of immunity-boosting flavonoids. Conversely, when the gene was overexpressed, those plants had stunted growth, …

… calls. Nearly 200 Terabases of data are expected to be generated for the accepted proposals, said Susannah Tringe, … Many fungi have beneficial symbiotic relationships with plants and bacteria; in many instances, fungal physiology is … “with unprecedented precision” the gene functional networks and regulatory networks of a single strain of  …