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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under standard conditions. As described in a recent issue of mSystems , scientists found that adding salt to the … provides engineers concrete targets for optimization. Many of the metabolic switches identified are shared across …
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SIPs with Standards
… SIP labwork and analysis can be very demanding.  The JGI offers SIP analysis to make these experiments accessible to … more reusable, and more insightful, for the future of studying microbial communities.   …
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The Megadata of Lake Mendota - Part 1: Many, Many Mers
… Lake Mendota sits right next to the University of Wisconsin, Madison. And Trina McMahon's lab has been sampling the microbes of that lake for over 20 years, to understand how the freshwater ecosystem works.  … So a few years ago, when they set out to analyze 500 metagenomes, it was the biggest project the JGI had ever put …
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The Megadata of Lake Mendota - Part 2: Souped Up Computing
… This series is the story of a giant metagenome assembly from Wisconsin’s Lake … large datasets with the assembler program MetaHipMer2. Oak Ridge National Lab is home to two supercomputers — Summit and Frontier — that process terabytes of data with MetaHipMer2. And the National Energy Research …
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The JGI announces FY25 awardees for our Community Science Program Annual Call
… is excited to announce the 18 scientists selected for our 2025 Community Science Program Annual Call. These projects … degradation.  “We are  very excited to see the outcome of the innovative research  being proposed by this year’s … CSP investigators,” said Tanja Woyke, Deputy Director of JGI’s User Programs. “Many of these projects are large in …
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Exploring Possibilities: 2022 JGI-UC Merced Interns
… And also specifically, it sparked my interest in bioformatics, so that’s what I’m gonna take with me to the … are a little bit stronger in computing, so I was kind of worried coming into the, the internship that maybe I didn’t have as good of skills as somebody else might have. But Robert, uh, Bob …
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EcoFAB 2025: Advancing Mechanistic Microbial Science Using Fabricated Ecosystems
… studies.  This conference is inspired by the vision of standardized fabricated ecosystems (EcoFABs) designed for precise manipulation and reproducible … the future of microbiome science. Organizers The EcoFAB 2025 Conference is organized by the EcoFAB Steering …
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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … to keep processes running smoothly. As reported August 26, 2021, in Nature Communications , researchers led by Hal … senior authors. “But this has been done most commonly in bacterial-based systems, and so one of the things that I …
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UC Merced Interns Reflect on Their JGI Summer Projects
… Over the course of eight weeks this past summer, 10 students from UC Merced … on research projects that contribute to the larger mission of the U.S. Department of Energy. Students also worked with … summer. The JGI-UC Merced internship program was founded in 2014 with the goal of inspiring students to embark on a …
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … to keep processes running smoothly. As  reported August 26, 2021, in  Nature Communications , researchers led by Hal … senior authors. “But this has been done most commonly in bacterial-based systems, and so one of the things that I …
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Toasting to the 2020 JGI-UC Merced Summer Internship Program
… UC Merced students and their JGI mentors toasted to the end of a nine-week virtual internship. The celebration was … JGI staff. According to Axel Visel and Zhong Wang, founders of this internship program, this was the largest turnout for … to date.  This summer internship program, which began in 2014, pairs undergraduate and graduate students from UC …
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Benjamin Cole
… University of California, San Diego (PhD, 2011) Rensselaer Polytechnic Institute (B.S., 2006) … List of pubs available on NCBI … Implementation of the Index of Cell Identity as an R package … Selected Publications … Software …
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