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… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … growth and reproduction—most organisms produce a set of "secondary metabolites," chemical compounds that often … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …

… analysis for synthetic biology and functional genomics. Prior to joining the JGI, he was a group lead at … National Laboratory where he focused on functional genomics of phototrophs. Through this and post-doctoral … B.Sc. (HONS) – University of Wales, Cardiff, Genetics Ph.D. – University of …

… Dr. Roux joined the JGI in 2017 to lead viral genomics research as part of the Metagenome Program. His responsibilities include the … of community-building efforts in the field of viral ecogenomics. For this role, Dr. Roux can rely on more than 10 … virus diversity and host interactions through global metagenomics. Nature 578, 432–436. …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …

… to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter scenes that came with crayons in various shades of white. To researchers searching for sequences of RNA … unpublished sequence data, was absolutely critical for the success of this effort and so was the acknowledgement of …

… in sequencing technologies have led to an abundance of microbial genomes becoming available to the global … in Science Advances , researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley …

… After studying the mechanism of action of antifungal natural products and their … deciphered function and host-symbiont interplay using metagenomics. Taking on a Research Scientist position in 2007, she switched gears from metagenomics to single-cell genomics, which is now her primary …

… A collaborative team led by researchers at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology (HudsonAlpha), and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, has discovered that the …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … and the  DOE Systems Biology Knowledgebase (KBase) . Metagenomics is the study of the microbial communities in the … with a host – with 23,000 MAGs. Modeling A New Path for Metagenomics Researchers Building upon these resources, KBase, a …

… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … N. crassa is the model organism for filamentous fungi, all of which contain a wide array of plant cell-wall degrading enzymes (PCWDEs) that allow …

… which specializes in genome improvement for plants. As part of that partnership, the JGI and HudsonAlpha researchers led … resource like this important to the field of plant genetics/genomics? Avinash: Having a better handle on the gene … them to diverse conditions is a time-consuming process. Successfully accomplishing this requires a diverse team of …

… For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one “petabase” – a quadrillion … has begun to the June dedication event of the Integrative Genomics Building—the new home of the JGI and KBase in the …