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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
…   The Science Scientists have fully decoded the genome of an oil-producing green alga, and demonstrated precise … gene targeting in the genome in the November 2025 issue of The Plant Cell. Auxenochlorella is an allodiploid hybrid … versus 120 MB in Chlamydomonas . With fewer redundant pathways and clearer gene-to-function relationships than …
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JGI Announces 2026 New Investigator Portfolio
… Kumar Gautam, Gareth Gillard, Audrey Goeckner, Jennifer Goff, Sarah Gonzalez Henao, Yang Hai, Julia G. Harenčár, … accepted proposals.  The New Investigator call , part of our  Community Science Program , allows us to work and … biological routes for critical minerals recovery, microbial pathways for high-value bioproducts, and plant–microbe …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… Survey of Setaria's natural diversity reveals seed dispersal in … Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … understanding its secondary metabolites and their pathways could fuel further agricultural applications for … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Olpidium, The Key to the Origin of Terrestrial Fungi
… Before 2006, Olpidium was one of the many obscure fungi of Chytridiomycota (the … attracted the attention of many mycologists with the two publications of the kingdom-wide, multi-gene phylogeny of … and analysis of their data at the time. Following the publication of their paper in 2011, Dr. Sekimoto from …
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Data Ecosystem
… The JGI is leveraging its current partnerships to offer new capabilities and resources to users through a BER … is discoverable and accessible. Linking the resources of powerful institutions like the JGI, KBase, NCBI, NMDC, … access to diverse datasets that deepen our understanding of how organisms interact with each other and with their …
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Evolution of a Fungal Gene Expression Regulator
… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … themselves can also be modified. The best-known example of a modified DNA base is a methylation of the base cytosine … the fungal tree of life, they tracked the evolution of 5mC pathways across 528 species. The researchers found that …
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Natural Prodcast Episode 7: Ben Shen
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a month now since …
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Silver age of GOLD introduces new features
… sequencing projects carried out at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley … a broad range of activities from proposal intake to publication. Information is also obtained and cross-checked …
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JGI@25: Using Team Science to Build Communities Around Data
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … genomes that are both large and complex. The first publication of a genome generated by the OGG initiative — … Filling in the Plant Tree of Life …
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An Integrated Dataset to Understand Ecosystem Interaction
… data set will help identify how different elements of the ecosystem interact and respond to changes in the … their genetic diversity. They hold economic value as both biofuel feedstock and their role in carbon sequestration. … microbial communities. This revealed key metabolic pathways and metabolites associated with the tree’s stress …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director … multiple types of payloads, such as individual genes, whole pathways, genome-editing tools, and reporters.” …
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