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Data Ecosystem
… users through a BER data ecosystem.  A data ecosystem is a connected resource where data from different organizations is discoverable and accessible. Linking the resources of powerful institutions like the JGI, KBase, NCBI, NMDC, EMSL and the Protein … specifically optimized for high-performance computing environments. …
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Hiroshi Otani
… Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly actinomycetes. His research activity is focused on developing and implementing new technologies and … in understanding how, when and why microbes decide to produce which metabolites. …
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How Filamentous Fungi Sense Food
… of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by the … proposal akin to the Encyclopedia of DNA Elements (ENCODE) project, which is aimed at determining the activity, … enriching the work being done as part of the 1000 Fungal Genomes Project. Funding for the project was also provided …
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JGI@25: Roots of a Mutualist Relationship
… In honor of the JGI's 25th anniversary in 2022, we have … (INRAE). Today, there are nearly 200 mycorrhizal fungal genomes publicly available on the fungal portal MycoCosm, … many sequenced through the JGI 1000 Fungal Genomes Project.       Francis Martin on the main impact of …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… As SIP experiments shed more light on microbial communities than ever before — especially with … substrates.  The idea is to improve the information produced in the next few decades of SIP experiments. “I’m … although reusability and reproducibility are still growing priorities for researchers in this area. …
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New and Improved: Eucalyptus Reference is Now Accessible
… assembly to support targeted tree breeding for the bioeconomy.   The Science Researchers report a new reference … eucalyptus in the July edition of the journal G3 Genes | Genomes | Genetics , with significant advances compared to … There are 900 species of eucalyptus. The trees are fast-growing plantation crops that supply wood and fiber for …
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DOE Metrics
… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal  Actual Total*   Actual % of Goal … counted once, even though an individual may have several projects/roles. Sequencing Quarter Total Bases (Trillions) … the interpretation of microbial, metagenomic, or plant genomes. [Download PDF] End-of-year Goal – Develop one new …
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You Can Move, But You Can’t Hide
… and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found … MGEs can affect a microbe’s ability to cycle nutrients or produce new chemicals. They can also affect ecosystems by … Resource (IMG/VR) , now with more than 15 million viral genomes. It was also key to developing the first version of …
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JGI announces 2024 Functional Genomics awardees
… year, the JGI accepts proposals for state-of-the-art functional genomics research from reseachers who translate genomic … Through our CSP Functional Genomics call , we look for projects that will leverage the JGI’s DNA synthesis and … in support of advancing the bioeconomy.  This year’s project goals range from improving crop productivity for …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… decoded the genome of an oil-producing green alga, and demonstrated precise gene targeting in the genome in the … two species, similar to a mule, but that is still able to reproduce asexually through mitosis. The alga naturally … also simplifies metabolic modeling and pathway optimization for enhanced lipid production. Also notable, researchers …
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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … the functions of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are microbial …
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Enlarging Windows into Understanding Gene Functions
… JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of … it can also serve as a stepping stone to studying many genomes simultaneously through multiDAP, which allows … Program (CSP) focuses on a fungal comparative ENCODE project known as FUNCODE. “We noticed a few years ago that …
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