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Metabolomics
… JGI by identifying the actual molecules present in an environment that influence system behavior.  Through this identification, metabolomics enables functional genome annotation, improves understanding of the role small … Find more details on the instrumentation we use and our methodology for …
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Mining Public Databases Yields Largest Map of Fungal Mitochondrial Genomes to Date
… JGI researchers nearly tripled the available fungal mitochondrial genome data, unlocking new potential for AI-driven studies … nearly 10,000 new annotations of fungal mitochondrial genomes — the DNA found inside mitochondria, the … The work conducted by the U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE Office …
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A One-Stop Shop for Analyzing Algal Genomes
… The PhycoCosm data portal allows anyone to freely investigate the genes of more than 100 algae. The Science Interested in the genomes of algae? You now have one place where you can … and enthusiasts to look deep into more than 100 algal genomes, compare them, and visualize supporting experimental …
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JGI announces 2023 CSP Functional Genomics awardees
… year, the JGI accepts proposals for state-of-the-art functional genomics research from potential users who need help … Through our CSP Functional Genomics call , we look for projects that will leverage the JGI’s DNA synthesis and omics capabilities to enhance understanding of gene and genome function.  Below find a list of the six researchers …
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Engagement Webinar: What Can You Do With An Approved CSP Functional Genomics Call Proposal?
… On July 8, JGI’s DNA Synthesis Science group held a  JGI Engagement: Accessing Functional Genomics Capabilities Webinar inviting researchers to … of the proposals. Upon approval from JGI reviewers, the DOE project managers review the proposals. The proposer of …
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Enlarging Windows into Understanding Gene Functions
… JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of … four letters represents an organism’s genetic code, or genome, which underlies physical features and functions. … Program (CSP) focuses on a fungal comparative ENCODE project known as FUNCODE. “We noticed a few years ago that …
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Microbial Genomics & Metagenomics (MGM) Workshop
… Registration has closed.  The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is offering a five-day workshop on … designed to familiarize users with the Integrated Microbial Genomes & Microbiomes (IMG/M) data and workflows for …
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Dan Rokhsar
… JGI in 2000 as the founding Associate Director for Computational Genomics, and led the computational efforts directed … human chromosomes. After successful completion of the Human Genome Project, Professor Dr. Rokhsar ’s team has continued to … AB in Physics, Princeton University, NJ MS in Theoretical Physics, Cornell …
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Boosting Small Molecule Production in Super “Soup”
… from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: … Program at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … the first time CRISPR-Cas9 had been used to modify a cell’s genome in order to create lysates with altered metabolic …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process all of … microorganisms had a close relationship. Then, using metagenomes and metatranscriptomes generated by the U.S. … ) conducted by the U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE Office …
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JGI announces final round of 2022 Functional Genomics awardees
… year, the JGI accepts proposals for state-of-the-art functional genomics research from potential users who need help … Through our CSP Functional Genomics call , we look for projects that will leverage the JGI’s DNA synthesis and omics capabilities to enhance understanding of gene and genome function.  Below find a list of the final six …
Learn more
Boosting Small Molecule Production in Super “Soup”
… from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Yeast strains engineered for the … Program at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … first time CRISPR-Cas9 had been used to modify a cell’s  genome in order to create lysates with altered metabolic …
Learn more

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