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… Institute (JGI), a DOE Office of Science User Facility. The sequences were then biochemically characterized by a team … to foreign genetic elements by incorporating short sequences from infecting viruses and phages. In the event of … the microbes use the genetic information encoded in CRISPR sequences to target the virus and release attack enzymes in …

… to the way many organisms function, they have a sense of why nitrogen metabolisms can be so varied.  As evolution has … It’s useful to differentiate these enzyme tools into two groups: core metabolism and specialized metabolism.  For … different Swiss Army knives — explaining a bit more about why and how nitrogen metabolism is so robust and varied.  …

… our tools with a widening circle of researchers. That’s why twice each year we look for novel research projects — …

… tool to correlate protein annotations with ratios of DNA sequence fragments from the ecosystems. Selecting a protein … Those similarities, based on their ratios of small DNA sequence fragments called tetranucleotides, are a way to … a large part of the creation of the tool. The team used two types: Linear Discriminant Analysis (LDA) and k-Nearest …

… Foundry, and the study’s senior author. In other proteins, two histidine residues can be found to sandwich an … of that machine — photosynthesizers’ DNA and RNA. These sequences provide a list of machine parts, and an idea of … the cell, Grosjean used the JGI-developed  guideRNA and Sequence Extraction Tool (gRNA-SeqRET) to produce knock-out …

… Spatafora of Oregon State University led the effort to sequence 1000 fungal genomes to create two reference genomes for all fungi families — essentially, … by more than 100 participants. Roughly 700 have been sequenced and annotated, representing 384 fungal families …

… AMGs in soil viruses thought to break down chitin, the gene sequences were cloned by the JGI.  The JGI’s DNA synthesis … genes and mutants. DOIs of publicly available chitosanase sequences were retrieved using the  JGI’s Integrated … and AMGs. It could spawn future research into understanding why these AMGs exist in the first place, and what function …

… from similar organisms, researchers have gained insights on why the dry rot ( Serpula lacrymans ) is so destructive in … Office of Science User Facility, compared the genomes of two strains of fungi Serpula lacrymans – var. lacrymans from … Serpula species, S. himantioides from Europe, that was sequenced and analyzed by the JGI. The researchers found …

… impacts of these viruses on microbiome processes is still limited. One key challenge is to complement diversity surveys …