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The More the Merrier: Making the Case for Plant Pan-genomes
… system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” with respect to their genomes. In their base state, they are diploids with two genome copies, one from each parent. Having three or more genome copies from additional parents or …
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Doubling Down on Known Protein Families
Using a novel computational approach, researchers confirm microbial diversity is wilder than ever. Imagine researchers exploring a dark room with a flashlight, only able to clearly …
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Pinning Down a Piece of Photosynthesis
By studying the structure and function of a cyanobacterial protein, … proteins — and its role in photosynthesis — in the cyanobacterium  Synechocystis . Through an array of experiments … produces this domain as a stand-alone protein, the cyanobacterium  Synechocystis . Working with  Synechocystis also …
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Boosting Small Molecule Production in Super “Soup”
Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as … on Carbon Flux and Future Directions The team reported producing BDO at the rate of 0.9 grams per Liter-hour in a …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … Methanogenic microorganisms therefore play a critical role in the global carbon cycle, and are of significant interest … which direction the enzyme these genes encode are used — so producing methane or consuming methane, those are already …
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Products
The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, DNA synthesis and pathway engineering Mass spectrometry based metabolomics Below is a …
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Tanja Woyke
After studying the mechanism of action of antifungal natural products and their derivatives during her Ph.D. in Microbiology at the Eberhard Karls … NASA Exobiology.  … Volland et al. 2022. A centimeter-long bacterium with DNA contained in metabolically active, …
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Training the Next Generation of Talent
New Graduate Internship Program Builds Bridges Between DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. … at academic level in a few years as it’s getting closer to producing trillion base data sets on daily basis.” As part …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… with the prospect of meta-analyses boosted by AI and Machine Learning — JGI researchers and collaborators work to create FAIR … of the Soil Microbiome  Science Focus Area (SFA), is producing hundreds of stable isotope probing genome-resolved …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… warm-adapted microbes edge polewards, they’d oust resident tiny algae. The cold polar oceans give rise to some of the … their base are microscopic, photosynthetic algae. But human-induced climate change , a new study suggests, is displacing … senior author of the study. “Prokaryotes are not capable of producing all the juicy proteins and lipids that eukaryotes …
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2025 NeLLi Symposium
Registration and Agenda Coming Soon!  Hosted by the DOE Joint Genome Institute, the University of Nevada, Las Vegas, and the …
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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of …
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