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… encoded in the genome sequence is part of the integrative science mission of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … genes are turned on is known as DNA affinity purification sequencing or DAP-seq. The technology was developed by Ronan …

… computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do … are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these viruses … of Energy Joint Genome Institute, a DOE Office of Science User Facility at Lawrence Berkeley National …

… diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get their name from the same … at Lentinula samples from around the world. By complete sequencing of 24 new mushroom genomes, and assembling … and transcriptome sequencing were enabled by the Community Science Program (CSP) at the U.S. Department of Energy (DOE) …

Laboratory.   On March 2, 2021, the Environmental Molecular Sciences Laboratory hosted a webinar to showcase how … of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence Berkeley National … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …

… others providing complementary expertise to advance the science and serve as impact multipliers . The JGI has a … through the Facilities Integrating Collaborations for User Science (FICUS) program.     …

Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … due to their difficulty and complexity, but we have been extremely pleased with Jeremy, Jane and their team. Many … you have to alter.’ Why should we invest in something that may not be an immediate benefit to us for a decade? We …

… helps ID novel interactions between bacteria and fungi The Science Researchers have successfully automated aspects of a … of Energy Joint Genome Institute, a DOE Office of Science User Facility at Lawrence Berkeley National … at a larger scale through downstream DNA purification and sequencing steps. Ultimately, researchers found their …

… transcription factors with their target genes. The Science Regulons are a group of genes that can be turned on … of regulon identification by in vitro transcription-sequencing (RIViT-seq) to facilitate the characterization of … coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions is part …

… it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays ) produces a plethora of antibiotics called zealexins. … cultivated for bioenergy. The zealexin synthesis pathway may be especially amenable to transfer into other plants …

… fungi can degrade the hardiest of plant components   The Science There are three main ingredients to tackle when it … perhaps the accepted narrative wasn’t quite accurate, and maybe anaerobic fungi living in soils or the guts of … for lignin deconstruction. (The JGI also conducted RNA sequencing and alignment to the reference fungal  genome . …

… to freely investigate the genes of more than 100 algae. The Science Interested in the genomes of algae? You now have one … Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … study DNA methylation, which gives clues to how an organism may tune gene expression; and investigate corresponding …