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Uncovering Novel Genomes from Earth’s Microbiomes
… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel … Because most microbes cannot be cultivated under laboratory conditions, their genomes can’t be sequenced using … over 500,000 existing genomes available at that time. “Looking across the tree of life, it’s striking how many …
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Crysten Blaby-Haas
… with Valérie de Crécy-Lagard on using comparative genomics to predict gene function in bacteria and leveraging molecular biology and reverse genetics to test those hypotheses. From 2011 – 2015, she worked with … National Research Service Award (NRSA) Individual Postdoctoral Fellow, expanding her experimental repertoire to …
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Fishing for Novel Cellulose Degraders
… A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of the most vital pieces … is a boxful of lures. Designed with feathers or wires to mimic an insect or a particular movement, each of these lures are the bait designed to attract specific catches. A similar technique has been …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from … capabilities, large-scale data, and professional expertise to support the global research community in studies of … and environmental systems. We optimize our service to the community through responsibly managing our people and …
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A Plantiful Future: Xiaohan Yang
… Xiaohan Yang, a scientist at Oak Ridge National Laboratory, believes they can. And, what’s more, that using gene editing technology to conscientiously mix traits of different plant species …
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Exploring the Diversity of the American Prairie’s Switchgrass
… ) has long been a tantalizing potential biofuel feedstock. But switchgrass has a complex genome and, as a … diversity. So, a team of scientists made an ambitious plan to begin to link the plant’s varying traits — height, biomass, …
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Georg Rath
… of life science and computational science with notable stops at NERSC, IMBA (Institute of Molecular Biotechnology, … Vienna, where he first stumbled from software development into building productive infrastructure in close collaboration … by LBNL, where possible, and enriching it, where necessary, to fit the needs of the dynamic environment that is JGI. …
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JGI Earth Month: Kjiersten Fagnan Reflects on Shelter-in-Place Effects
… March 17, 2020, a shelter-in-place order for all residents took effect in six San Francisco Bay Area counties. The JGI, located at Lawrence Berkeley National Laboratory, is located in one of those counties. The … User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE …
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Forest Fungi, Seagrass, and a New View of Symbiosis
… Three stories of JGI-supported research, connected to nutrient cycles. Francis Martin and Lucas Auer discuss … work on communities of forest floor fungi. Allison Joy looks into seagrass meadows' carbon sequestration with …
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JGI@25: Building a Better Bean
… that showcase our collaborations and capabilities to enable great science that will help solve energy and … challenges. While a hill of beans may not seem to amount to much, the common bean (Phaseolus vulgaris) is actually a … P. vulgaris on Phytozome …
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EcoFAB 2025: Advancing Mechanistic Microbial Science Using Fabricated Ecosystems
… at the conference venue This inaugural event will bring together researchers across major ecosystems and disciplines who are developing and applying laboratory ecosystems to help transition microbiome science from largely …
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Digging into Microbial Ecosystems Deep Underground
… communities deep underground, and before the pandemic, they took the JGI on a sampling field trip. One of the questions they’re looking at: the role viral infection may play in other … (FICUS) . Through FICUS, the researchers have tapped into the resources and capabilities of both the JGI and the …
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