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Uncovering Novel Genomes from Earth’s Microbiomes
… analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple … analyzed.” Emiley Eloe-Fadrosh, head of the  JGI Metagenome Program and senior author on the study elaborated on … she said. Listen to study co-author Dan Udwary talk about genome mining using the GEM catalog in  this episode …
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Expression of macromolecular organic nitrogen degrading enzymes identifies potential mediators of soil organic N availability to an annual grass
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Examples: Successful LOIs & Submissions
… of successful Letters of Intent to our Community Science Program Large-Scale Call, as well as successful submissions … Genomics, and Facilities Integrating Collaborations for User Science calls. These documents have been shared with … insights in lignin biosynthetic pathway edited populus …
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JGI@25: From Life at the Extremes to Editing Genomes
… ecosystems around the world, conducting iterative searches using statistical analyses to continuously refine and … and Management.” So begins a passage from Doudna’s book about her meeting with Banfield. (Banfield’s recounting of … doi: 10.1016/j.molcel.2018.12.015. Harrington LB et al. Programmed DNA destruction by miniature CRISPR-Cas14 …
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A Genome-Wide Survey of Switchgrass Genome Structure and Organization
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Multiple whole-genome alignments without a reference organism
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Telomere Organization in the Ligninolytic Basidiomycete Pleurotus ostreatus▿ †
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring … on mining prokaryotic viruses together, learned from JGI’s Nikos Kyrpides that his Microbiome Data Science group was also … of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence Berkeley National …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… be single bacterial cells, visible to the naked eye. The unusual size is notable because bacteria aren’t usually … couple of years, and realized it was a sulfur-oxidizing prokaryote. Silvina Gonzalez-Rizzo, an associate professor … explained. “This kind of discovery opens new questions about bacterial morphotypes that have never been studied …
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A Natural Mechanism Can Turbocharge Viral Evolution
… The Science The first step in the deadly dance between a virus and microbial cell is an embrace. For a virus with a “head-tail” morphology, this means using proteins … cells or hosts. This ability isn’t enough to make them super viruses, though, said Roux. There’s a gauntlet of …
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Synthetic Biology Informatics Group
… maintain software that support the JGI’s Synthetic Biology Program .  Representative software includes: gRNA-SeqRET , …
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An Automated Tool for Assessing Virus Data Quality
… CheckV can help researchers assess virus sequence fragments and data quality. The Science Through … first author in the Microbiome Data Science group led by Nikos Kyrpides. To demonstrate its utility, Nayfach applied CheckV …
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