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Extracting the Secrets of Secondary Metabolites
… CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  … Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … in overcoming this obstacle when it hit the scene in 2019. Now, that power is poised to grow exponentially by …
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Degradation of Bunker C Fuel Oil by White-Rot Fungi in Sawdust Cultures Suggests Potential Applications in Bioremediation
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From Berkeley to Binghamton: Tracking Strawberry Evolution
… In the summer of 2015, Adam Session was a postdoc working at the DOE Joint Genome Institute with Dan Rokhsar, who also holds a joint … New York. He and Rokhsar have  recently published a Nature Communications paper that builds off their early …
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A Natural Mechanism Can Turbocharge Viral Evolution
… ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating … by scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … prey. The Impact This research provides a much more comprehensive understanding of how a fundamental mechanism …
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Genome sequences of key bacterial symbionts of entomopathogenic nematodes: Xenorhabdus cabanillasii DSM17905, Xenorhabdus ehlersii DSM16337, Xenorhabdus japonica DSM16522, Xenorhabdus koppenhoeferii DSM18168, and Xenorhabdus mauleonii DSM17908
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JGI Workshop at SIMB NP Meeting
… of biosynthetic gene clusters (BGCs) in native hosts, the complexity of cloning and expressing a given BGC in various hosts, availability of sequenced genomes, and computing resources needed to predict BGCs from available genome sequences. The DOE Joint Genome Institute (JGI), a …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… processes both carbon and nitrogen. This research team combined computational and experimental approaches to look at how this enzyme family evolved across 90 species. “One unique thing about this work was our focus … as well as the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Simulation of Deepwater Horizon oil plume reveals substrate specialization within a complex community of hydrocarbon degraders
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Pinning Down a Piece of Photosynthesis
… scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … share. The end result was a list of genes, termed  The GreenCut2 Resource . It details 597 genes coding for proteins that are unique to … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Enlarging Windows into Understanding Gene Functions
… T, C and G appearing over and over in a dizzying array of combinations, are unremarkable, save perhaps for the absence … four letters represents an organism’s genetic code, or genome, which underlies physical features and functions. … Technologies Group. In an article published November 25, 2021 in Nature Methods , JGI researchers led by co-first …
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A Mentor’s Perspective on Training the Next Generation
… Over the years, hundreds of interns have come to the JGI from all parts of the globe to gain lab …
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JGI Hosts GPU Hackathon in May
… WHEN: May 6-10, 2019 WHERE: JGI With DOE investments in graphical processing unit (GPU)-based high-performance computing resources, an upcoming hackathon led by the Oak … (OLCF), NVIDIA, and the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user …
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