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… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. Last year, the JGI surpassed three Petabases of data sequenced — that’s three-quadrillion base pairs of DNA sequence! To meet this “ data tsunami ,” as Kathy …

… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… A new view into a symbiosis could offer benefits to address climate change: pulling atmospheric carbon into soil and boosting biofuel feedstocks with less fertilizer. For millions of years, underground fungi have lived in symbiosis with … Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy …

… A nuanced understanding of peat moss drives insight into carbon storage   The Science Boggy peatlands, which hold much of the Earth’s carbon as well as material that can be converted to energy, are made up heavily of sphagnum mosses.  New research identifies sex chromosomes …

… A fungus relies on bacteria to regulate key components of its reproductive machinery The Science To better … , is recognized as a mutualist, where both species of organism benefit from association, but was predicted to … researchers also generated the first transcriptomic dataset of sexual reproduction in early fungi and discovered genes …

… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under standard conditions. As described in a recent issue of mSystems , scientists found that adding salt to the … provides engineers concrete targets for optimization. Many of the metabolic switches identified are shared across …

… get any sunlight, and yet they still support a unique array of microorganisms adapted to living in extreme conditions. … five oceanic regions. In doing so, they found a high degree of variability in the types of microorganisms that inhabit these sites, as well as the …

… (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … to help researchers assess and improve the quality of metagenome-assembled viral genomes . The Impact The … DNA sequencing can help scientist to recover the genomes of these viruses and associate them with their microbial …

… The Science Researchers have successfully automated aspects of a commonly-used process for studying microbial … with results published in the  November 2022 issue of Microbiome . High-throughput stable isotope probing (SIP) … and improve results. Applying this method to the study of a particular fungi, researchers identified novel …

… di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and interacts with cell signaling networks that … role in regulating microbial cellulose production and biofilm formation, which affects a number of environments, including plants, soil, and the gut. To …

… begins at the forest floor. Within the soil, a microbiome of bacteria, viruses and fungi process carbon and nitrogen, … the microbes within the soil. To get a clearer picture of how burned ecosystems return to health, researchers have taken a look at microbial genomes across a spectrum of burned soils. By connecting microbial genes with …

… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene expression allowed researchers to identify variations of essential genes in metabolic networks that were missed … This work was funded by the Air Force Office of Scientific Research under Award No. …