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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies. While … Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due …
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Fungus Fuels Tree Growth
… Researchers start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.   … partnered with the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … for the DOE. The work conducted by the DOE Joint Genome Institute, a DOE Office of Science User Facility, is …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… made strides in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c …
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Year in Review: JGI’s 2018 Progress Report Available Now
… The latest edition of the JGI Progress Report highlights notable research and scientific collaborations in 2018. The cover is an image of Mono Lake, a saline …
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Rex Malmstrom
… is a Staff Scientist and leader of the Microscale Applications group. Before joining the JGI in 2010, he made the first ever measurements of in situ growth rates and carbon consumption of SAR11 bacteria, the most abundant … genomics pipeline that provides JGI users access to the genomes of uncultured microbes.  His group also handles the …
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JGI announces second round of 2023 New Investigator awardees
… right: [above] Emma Bell, Mallory Choudoir, Sneha Couvillion, Tobin Hammer, Christina Hazard, Rachel Mackelprang, … eager to work and share our tools with a widening circle of researchers. That’s why twice each year we look for novel research projects — aligned with DOE missions and from PIs …
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Toward More Efficient Artificial Photosynthesis
… Chloroplast mimic a platform to capture and utilize carbon in a synthetic fixation cycle. The Science Chloroplasts … convert them into energy that is then stored. A team led by researchers at the Max Planck Institute (MPI) for … Program (CSP) of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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JGI Welcomes New UEC Members
… (UEC) represents the JGI user community and is responsible for providing input and advice on JGI policies and practices that affect users and their … were nominated, representing a breadth of institutions, research topics and career stages. The election period …
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JGI announces 2024 New Investigator portfolio
… eager to work and share our tools with a widening circle of researchers. That’s why each year we look for novel research projects — aligned with DOE missions and from PIs who have not led any previously-accepted …
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EcoFAB 2025: Advancing Mechanistic Microbial Science Using Fabricated Ecosystems
… Register here Book your stay at the conference venue This inaugural event will bring together researchers across major ecosystems and disciplines who are … advancing standardized fabricated ecosystems for microbiome research. Contact If you have questions or would like access …
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Team Science Reveals Important Protein in Poplar
… bioenergy crops The Science Scientists at Brookhaven National Laboratory (BNL) led a team that  identified a protein … Plants for the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … in the engineered plants while a Molecular Foundry researcher provided insights into how the regulatory …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … ability to fine-tune the level of gene expression allowed researchers to identify variations of essential genes in … researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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