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… a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods …

… for large-scale in situ gene expression analysis in multicellular organisms. During his postdoctoral training at … for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of thousands of genetic … LA, Visel A (2013). Fine tuning of craniofacial morphology by distant-acting enhancers. Science 342, 1241006. Visel A …

… twilight zone, to the continuous pressure of the dark abyss, 4000 m (2.5 miles) deep. Scientists have wondered, how … In order to determine the genome structure of SAR324 cells and their gene expression, the team then sequenced community genomes and expressed gene transcripts (metagenomes, …

Rumen microbes have the ability to break down hardy plant cell walls and therefore hold clues to how humans could do … scientists to study microorganisms that can’t be cultured by analyzing and then extrapolating data obtained from … coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias …

… alga  Chlamydomonas reinhardtii , one of the JGI’s Flagship genomes. She and her colleagues have generated a … mutant library in Chlamy, as the alga is colloquially known by researchers. A missing gene from this mutant library … group, one of the four proposals selected is led by Eoin Brodie of Lawrence Berkeley National Laboratory …

… page of that book. Published online September 28, 2022, in Cell , a team led by researchers at Tel Aviv University in Israel, the … datasets from the JGI’s Integrated Microbial Genomes & Microbiomes (IMG/M) system. “We then looked into …

A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of … specific catches. A similar technique has been developed by researchers led by Tanja Woyke at the U.S. Department of … To validate the predicted cellulases from their captured genomes, the team then used DNA synthesis and cloning, …

… of the comparative analysis platforms for microbial genomes and metagenomes (IMG). He became the Metagenomics Program head in … global RNA virome reveals diverse clades of bacteriophages. Cell . 185(21):4023-4037 Nayfach S, et al. …

July 22, 2019, in  Nature Microbiology , a team led by scientists at the U.S. Department of Energy (DOE) Joint … are filamentous viruses with small, single-stranded DNA genomes and a unique chronic infection cycle. “We’re not … are stealth agents that can enter and exit through the cell membrane without lysing the bacterial host. They can …

… decomposition. She’s also participated in the 1000 Fungal Genomes Project and has an interest in cross-disciplinary … On the UEC she intends to represent the user community by providing input on JGI policies and capabilities that … Her research focus is genetically engineering the plant cell wall to address dairy sustainability challenges. She’s …