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New Tricks with Old Bones
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How to Target a Microbial Needle within a Community Haystack
… for capturing the genetic make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at the Max Planck Institute (MPI) for Marine Microbiology has developed, tested … sequences can be even more challenging. To overcome this hurdle, a team led by Bernhard Fuchs and his postdoctoral …
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Rex Malmstrom
… the JGI in 2010, he made the first ever measurements of in situ growth rates and carbon consumption of SAR11 bacteria, … genetic material, thus bypassing the need to culture these microbes in the lab. After joining the JGI, he formed the … require fluorescence activated cell sorting and non-standard molecular protocols.  Finally, his team utilizes new …
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Green Algae Reveal One mRNA Encodes Many Proteins
… mRNA – in two species of green algae, Chlamydomonas reinhardtii and Chromochloris zofingiensis . “I was scrutinizing … what looked like mistakes by the gene prediction algorithms. I decided to dig in a little deeper, and realized what was really happening,” … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at …
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JGI@25: Building a Better Bean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great science that will help solve energy … molecular markers, and slow-darkening has become standard for pinto beans. These beans cook faster, retain their …
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Four Researchers Join JGI User Executive Committee
… Four researchers have been elected to the User Executive Committee of the Joint Genome Institute, a Department of Energy … Bik is an associate professor at the University of Georgia whose work is at the interface between biology and computer … focuses on the evolution, ecology, genomics and function of microbes and microbiomes, especially those found in …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… avenues for using bacteria to produce ethylene and more.  Microbes excel at recycling the abundant miscellanea of … in the biotechnology innovation ecosystem. “At JGI, we’ve done the synthesis, metagenome mining, all the way from … metallocofactor as  seen with nitrogenase M-clusters, whose precise identity is of key interest. With this …
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Extracting the Secrets of Secondary Metabolites
… gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth yet essential … to integrate large genetic payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers … are microbial compounds produced in response to hardship or competition. They make up the foundation for a …
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From Competition to Cooperation
… able to carry out a broader analysis than had ever been done before to look at how multiple forest fungi have … independently evolved to establish symbiotic relationships with plants (mycorrhizae), and particularly how fungi that … Having these datasets will assist researchers in moving toward functional genomics studies to learn more about the inner …
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Boosting Small Molecule Production in Super “Soup”
… (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to make … one of the study’s senior authors. “But this has been done most commonly in bacterial-based systems, and so one of … their ability to redirect the carbon in the cells toward particular pathways. In this case, towards BDO and away …
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Robert Bowers
… uses single-cell genomics and metagenomics to explore how microbes influence people and the environment. This includes studying the diversity, physiology and community ecology of microbes sampled from the natural environment. …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… enzymes play second fiddle to those from fungi when it comes to breaking down tough plant fibers. The Science … nitrogen-metabolizing enzymes are abundant, and to which microbes they belong. This study provides further insights … team was able to identify enzymes in the soil and who made them. Based on data reported in the April issue of …
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