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2022 Progress Report
… Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems …
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The Power of One, Amplified
… A preview of how large-scale single cell genomics complements metagenomics studies. The … between the analyzed community members. The Impact Though microbes help regulate the planet’s nutrient cycles and are … of tens of thousands of previously unknown and uncultivated microbes through metagenomics. Such techniques take …
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Simon Roux Named 2025 ASM Microbiome Data Prize Awardee
… Congratulations to US Department of Energy (DOE) Joint Genome Institute (JGI) staff scientist Simon Roux , who was … analysis to better characterize how viruses infect soil microbes and influence how soil ecosystems function. He was …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… With a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of … easily in the lab. To access the genomes of uncultured  microbes , scientists usually employ two different methods; … U.S. Department of Energy Joint Genome Institute (https:// ror.org/04xm1d337), a DOE …
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What Happens To a Rainforest When You Dial Up Drought?
… Rainforests store a big fraction of all the carbon on Earth, and soil microbes play a key role in pulling that carbon out of the atmosphere. This episode, …
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Supercharging SIP in the Fungal Hyphosphere
… High-throughput stable isotope probing helps ID novel interactions between bacteria and fungi … it. The isotopes are incorporated into the DNA of specific microbes who consume the labeled food or water. Later, their … which microorganisms used the labeled substance and which microbes did not. This is normally an arduous wet lab …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… In honor of the JGI's 25th anniversary in 2022, we have … of course, the cells of other organisms. As they infect microbes like bacteria, algae and protists, all kinds of … and in your data, and they’re probably influencing the microbes there,” said Simon Roux , the Viral Genomics Group …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… Team develops a computational pipeline to sift and characterize RNA virus sequences.  A zoo … Computational Sieves to Filter Sequences There are more microbes on the planet than particles in a handful of dirt, and viruses vastly outnumber the microbes. Advances in sequencing technologies and …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users … users can leverage to create a more complete picture of how microbes control useful chemistry in other organisms.  … the power of combining multiple omics methods to decode how microbes control chemical production. These efforts support …
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Year in Review: JGI’s 2018 Progress Report Available Now
… highlights notable research and scientific collaborations in 2018. The cover is an image of Mono Lake, a saline soda lake east of California’s Yosemite National Park, taken by JGI’s own Jon Bertsch. Microbes isolated from Mono Lake were sequenced by the JGI …
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SIPs with Standards
… Stable Isotope Probing (SIP) is a powerful technique for studying microbial communities. These experiments can show which microbes are handling specific nutrients, or what they're …
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Microbial Metagenomes Across a Complete Phytoplankton Bloom Cycle: High-Resolution Sampling Every 4 Hours Over 22 Days
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