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… Through advances in sequencing technologies and computational approaches, more and more virus sequences are being … recovered and identified from environmental samples (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a previous …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, is …

… analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures … 5mC is an important piece of how they regulate their genomes, but is not well understood in fungi. A team of …

… This webinar focused on how the JGI employs single-molecule, long-read DNA sequences to aid with genome assembly and transcriptome analysis of microbial, … to DNA methylation analysis as well as improving metagenome assemblies. Q&A from the Webinar: Input & sequencing …

… that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … human and ecosystem health. But bacteria often fail to express their BGC molecules in the lab. By engineering …

… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes … This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … in the Synthetic Biology special issue, Modular cell-free expression plasmids to accelerate biological design in cells , …

… A two-day kick-off meeting held at Lawrence Berkeley National Laboratory (Berkeley Lab) marked the visit of an … Research Center One Health Ruhr (OHR), and the DOE Joint Genome Institute (JGI), Molecular Biophysics and Integrated … Lab. Commenting on the visit, JGI Director Nigel Mouncey expressed enthusiasm about the potential of this collaboration …

… help improve crop yields.  The Science The fire moss Ceratodon purpureus is a short plant with a complex genome . Now, high-quality reference genome sequences of the male and female plants, each … The work conducted by the U.S. Department of Energy Joint Genome Institute was supported by the Office of Science of …

… Sorghum genome serves as a reference for the highly complex sugarcane genome . The Science Most species are diploids and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple … For the portion of the work conducted by the Joint Genome Institute and the Joint BioEnergy Institute, support …