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… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … at the time, there was maybe, yeah, several thousand fully sequenced biosynthetic gene clusters from organisms that had …

… algae in a container with access to sunlight, water and carbon dioxide so they can grow, and then harvest for use as … Researchers collaborating across multiple institutions have sequenced and analyzed the genome of an alga that thrives in … expertise at the National Labs to screen, characterize, sequence and then analyze the genomes and multi-omics …

… of genomics and JGI scientists are developing cutting edge technologies to answer our most pressing problems. I’m very … focuses on the roles of microbial communities in wetland carbon cycling and the interactions of plants with their … Rambo will be studying the influence of viruses on carbon cycling in coastal mangroves. The work complements an …

… with a complex genome . Now, high-quality reference genome sequences of the male and female plants, each representing a … assemblies highlight the multiple advances in sequencing technologies applied to the effort. The Impact Found on all … sequence the fire moss genomes ran the gamut of sequencing technologies, from making a bacterial artificial chromosome …

… Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … Efforts include developing innovative screening technologies and computational tools that enhance biofuel … combinatorial construct variations. These constructs are subsequently synthesized and tested for their ability to …

… with a view to developing a deeper understanding of sequence-based gene function. … with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria Nature Communications 15(1) 3167. 2024 Simirenko et al ., gRNA-SeqRET: a universal tool for targeted and genome-scale gRNA …

… and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better understand the … and computational approach, we employ various omics technologies, strain engineering and experimental … single-cell profiling methods, including single-cell RNA-seq, single-cell ATAC-seq, and spatial transcriptomics to …

… of living. The Impact Microbes help regulate the global carbon cycle — fixing, transforming, and respiring carbon. Understanding the metabolisms that SAR324 and other … of SAR324 cells and their gene expression, the team then sequenced community genomes and expressed gene transcripts …

… created in 1997 to unite the expertise and resources in DNA sequencing, informatics, and technology development … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … accomplishment, the JGI went on to advance basic science by sequencing scores of microbial species as well as several …

… in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures and … methylation of the base cytosine at the 5th position on its carbon ring, or 5mC. In many organisms, 5mC is an important … methyltransferase (MTase) variants. Using new sequencing technologies for producing both reference genomes and …

… approved proposal – including the submission of samples for sequencing, or the submission of sequencing data for synthesis – the DOE requires that all …

… Rainforests store a big fraction of all the carbon on Earth, and soil microbes play a key role in pulling that carbon out of the atmosphere. This episode, researchers take …