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Rex Malmstrom
… the JGI in 2010, he made the first ever measurements of in situ growth rates and carbon consumption of SAR11 bacteria, … genetic material, thus bypassing the need to culture these microbes in the lab. After joining the JGI, he formed the … require fluorescence activated cell sorting and non-standard molecular protocols.  Finally, his team utilizes new …
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Green Algae Reveal One mRNA Encodes Many Proteins
… mRNA – in two species of green algae, Chlamydomonas reinhardtii and Chromochloris zofingiensis . “I was scrutinizing … what looked like mistakes by the gene prediction algorithms. I decided to dig in a little deeper, and realized what was really happening,” …
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Robert Bowers
… uses single-cell genomics and metagenomics to explore how microbes influence people and the environment. This includes studying the diversity, physiology and community ecology of microbes sampled from the natural environment. …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located … collaborative research initiatives.” Yasuo Yoshikuni , who heads the JGI DNA Synthesis Science Program and was the … on thiolases, a superfamily of enzymes found only in microbes, which make carbon-carbon bonds. This ability is …
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Boosting Small Molecule Production in Super “Soup”
… (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to make … one of the study’s senior authors. “But this has been done most commonly in bacterial-based systems, and so one of … their ability to redirect the carbon in the cells toward particular pathways. In this case, towards BDO and away …
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From Competition to Cooperation
… able to carry out a broader analysis than had ever been done before to look at how multiple forest fungi have … independently evolved to establish symbiotic relationships with plants (mycorrhizae), and particularly how fungi that … Having these datasets will assist researchers in moving toward functional genomics studies to learn more about the inner …
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Extracting the Secrets of Secondary Metabolites
… gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth yet essential … to integrate large genetic payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers … are microbial compounds produced in response to hardship or competition. They make up the foundation for a …
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Identifying the Microbial Cleanup Crew at a Superfund Site
Analysis reveals the microbial community involved in a bioremediation effort. The Science In … by Congress in 1980 for Superfund sites which are hazardous waste areas that require cleanup and long-term … to bioremediation efforts for decades. Identifying resident microbes that can help bioremediate toxic substances has led …
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DOE JGI Metagenome Workflow
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Adam Reisselman on being a 2016 DOE Computational Science Graduate Fellow
… growing need for science and technology professionals with advanced computer skills. During the summer of 2016,  DOE CGSF recipient Adam Riesselman of Harvard University worked with DOE JGI's Sam Deutsch. Learn more about the …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
Understanding the shared genetic toolkit of ancestral and present-day plants The Science In a … polymorpha. Commonly known as liverwort, this was done to gain insights into gene families involved in … genes in more complex plants that could be applied toward DOE-relevant bioenergy and environmental interests.  …
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JGI Pitches 2022 Visiting Faculty Program Collaborations
Berkeley National Laboratory (Berkeley Lab) hosted a pitch event promoting fully-supported summer research … and travel expenses, both for faculty members and students who participate. The researchers who pitched potential collaborations were: Simon Roux and …
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