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2024 Progress Report
… Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE … for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic capabilities, … A record number of primary users — 2,456 — had active proposals with us, along with …
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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach … by a team of scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National …
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De novo DNA synthesis using polymerase-nucleotide conjugates
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Strain Engineering
… The focus of this group, in recent years, has been to bring … little to no genetic tools enabling heterologous expression and functional exploration.  The developed strains represent an additional phase of user-accessible project types, in which DNA-based molecules …
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RECAP: Multi-Omic Journeys with 2023 JGI Annual Meeting Keynotes
… 21-23, 2023, attendees joined the JGI Annual Genomics of Energy & Environment Meeting.  A wide array of invited … to the worldwide scientific community through its  User Programs on a competitive, peer-reviewed basis. … in the earth’s soils. While she admits that it “0.25% doesn’t seem like a lot (referring to the abundance of …
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Nick Everson
… Mr. Everson rejoined the JGI in 2020  and leads all aspects of JGI … after serving as the Chief Operating Officer of the DOE Joint Bioenergy Institute and the Operations Deputy for … resource and provides advice and counsel regarding current DOE, national laboratory, and UC policies and procedures …
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Len Pennacchio
… In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging … Len Pennacchio is the JGI's Deputy of Genomic Technologies. oClick to learn more about the offerings and capabilities we offer JGI users to help advance their science. …
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Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale
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Pinning Down a Piece of Photosynthesis
… By studying the structure and function of a cyanobacterial protein, researchers have new insights … an array of experiments at universities and national user facilities, researchers found that this protein detects … is a research scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. … computing infrastructure and analysis. This way, JGI users — both primary, data-generating users, as well as … effort. For example, with support from the  Exascale Computing Project , the JGI — along with the National …
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Comparative Genomics Using the Integrated Microbial Genomes and Microbiomes (IMG/M) System: A Deinococcus Use Case
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how … plant lineages. Aligning with U.S. Department of Energy (DOE) interests, this advancement holds the potential to … DOE Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National …
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